Defining multistep cell fate decision pathways during pancreatic development at single-cell resolution

This study provides key insights into the regulatory mechanisms underlying cell fate choice and stepwise cell fate commitment and can be used as a resource to guide the induction of functional islet lineage cells from stem cells in vitro.

Source: EMBO Journal - April 14, 2019 Category: Molecular Biology Authors: Yu, X.-X., Qiu, W.-L., Yang, L., Zhang, Y., He, M.-Y., Li, L.-C., Xu, C.-R. Tags: Development & Differentiation, Methods & Resources, Systems & Computational Biology Source Type: research