After NY Supreme Court strikes down Rockland County's ban against the unvaccinated, Bill de Blasio declares new "public health emergency," orders mandatory vaccinations for everyone

(Natural News) In response to the Supreme Court of New York’s recent overturning of the unconstitutional “ban” on all unvaccinated people that was imposed in Rockland County, New York City Mayor Bill de Blasio declared his own “public health emergency,” mandating that people in certain parts of Williamsburg who were potentially exposed to the virus...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Conclusions: Antidengue NAb levels can be boosted to levels at least as high as, or higher than those observed after completion of the primary 3-dose series, with an additional dose of CYD-TDV 4–5 years after the standard 3-dose vaccination schedule.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Conclusions: RV vaccination using RotaTeq did not alter the occurrence of DM1 but decreased the prevalence of CD in childhood and adolescence. We propose that wild-type RV may trigger CD and the triggering effect can be prevented or reduced by RV vaccination.
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Vaccine Reports Source Type: research
Conclusions: From 2011 to 2016, influenza-associated SARI hospitalization rates in children aged younger than 5 years of age in Suzhou, China, were high, particularly among children 0–5 months of age. Higher hospitalization rates were observed in years where the predominant circulating virus was influenza A/H3N2. Immunization for children> 6 months, and maternal and caregiver immunization for those
Source: The Pediatric Infectious Disease Journal - Category: Infectious Diseases Tags: Original Studies Source Type: research
The Epstein-Barr virus (EBV) is one of the predominant tumor viruses in humans, but so far no therapeutic or prophylactic vaccination against this transforming pathogen is available. We demonstrated that heterologous prime-boost vaccination with the nuclear antigen 1 of EBV (EBNA1), either targeted to the DEC205 receptor on DCs or expressed from a recombinant modified vaccinia virus Ankara (MVA) vector, improved priming of antigen-specific CD4+ T cell help. This help supported the expansion and maintenance of EBNA1-specific CD8+ T cells that are most efficiently primed by recombinant adenoviruses that encode EBNA1. These c...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
The Epstein-Barr virus (EBV) is estimated to infect a large part of the population and is associated with a variety of human tumors; therefore, EBV is an important target for vaccine development. In this issue of the JCI, Rühl et al. developed a promising heterologous prime-boost vaccination strategy for EBV-associated malignancies and symptomatic primary infection. The authors show that two prime-boost regimens, using either dendritic cells or an adenovirus approach targeting nuclear antigen EBNA1 followed by a modified vaccinia virus Ankara (MVA) booster, induced significant T cell–mediated, EBV-specific immun...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
In this study, herpes virus serological status and T cell, B cell, NK cell and monocyte populations were investigated in 251 ME/CFS patients, including 54 who were severely affected, and compared with those from 107 healthy participants and with 46 patients with Multiple Sclerosis. There were no differences in seroprevalence for six human herpes viruses between ME/CFS and healthy controls, although seroprevalence for the Epstein-Barr virus was higher in multiple sclerosis patients. Contrary to previous reports, no significant differences were observed in NK cell numbers, subtype proportions or in vitro responsiveness betwe...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
This study indicates that targeting of epitopes by human adaptive immunity is to some extent directed by defined thermodynamic principles. The proposed framework also has a practical implication in that it may enable to more efficiently prioritize epitope candidates highly prone to T cell recognition in multiple individuals, warranting prospective validation across different cohorts. Introduction T cell epitopes bound to major histocompatibility complex [MHC; also called the human leukocyte antigen (HLA) in humans] molecules activate T cells to initiate subsequent immunological orchestration (1–3). MHC class ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
We describe here a powerful method for identifying B cells that recognize membrane antigens expressed on cells. The technique depends on two characteristics of the interaction between a B cell and an antigen-expressing cell: antigen-receptor-mediated extraction of antigen from the membrane of the target cell, and B cell activation. We developed the method using influenza hemagglutinin as a model viral membrane antigen, and tested it using acetylcholine receptor (AChR) as a model membrane autoantigen. The technique involves co-culturing B cells with adherent, bioorthogonally labeled cells expressing GFP-tagged antigen, and ...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Ye Chean Teh1,2, Jeak Ling Ding2, Lai Guan Ng1,3,4 and Shu Zhen Chong1* 1Functional Immune Imaging, Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Biopolis, Singapore 2Department of Biological Sciences, National University of Singapore (NUS), Singapore, Singapore 3Department of Microbiology &Immunology, Immunology Programme, Life Science Institute, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore 4School of Biological Sciences, Nanyang Technological University, Singapore, Singapore Monocytes are a subset of cells that are ca...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Vega Masignani1, Mariagrazia Pizza1 and E. Richard Moxon2* 1GSK Vaccines, Siena, Italy 2Department of Pediatrics, Oxford University, Oxford, United Kingdom The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with the classical hypothesis-driven laboratory-based analysis of microbes to identify components to elicit protective immunity. This radical change in scientific direction and action in vaccine research is captured in the term reverse vaccinology. The complete genome sequence of an isolate of Neisseria meningitidis serogroup B (MenB) was systematically analyzed to identify prot...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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