Manage your cholesterol levels while you're still young to lower your risk of heart problems as you age, advises study

(Natural News) Having high cholesterol levels is usually a problem for older adults. However, young people are now encouraged to watch their cholesterol levels as well. This is because a new study found that having high levels of low-density lipoprotein (LDL) cholesterol at a young age can become a huge problem later in life. Published...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news

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Publication date: Available online 19 April 2019Source: Chemico-Biological InteractionsAuthor(s): Susmita Barman, Krishnapura SrinivasanAbstractZinc depletion during diabetes postulates a role for zinc nutrition in the management of associated complications. The present study evaluated zinc supplementation for countering the compromised intestinal integrity through moderation of oxidative stress and suppression of stress-stimulated inflammatory proliferation in streptozotocin-induced diabetic rats. Diabetic rats were provided with supplemental zinc for six weeks (5 and 10-times of normal level). Supplemental zinc nurtured ...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
Publication date: July 2019Source: Phytochemistry, Volume 163Author(s): Ana Cristina Jaramillo-Madrid, Justin Ashworth, Michele Fabris, Peter J. RalphAbstractDiatoms are abundant unicellular marine photosynthetic algae that have genetically diversified their physiology and metabolism while adapting to numerous environments. The metabolic repertoire of diatoms presents opportunities to characterise the biosynthesis and production of new and potentially valuable microalgal compounds, including sterols. Sterols of plant origin, known as phytosterols, have been studied for health benefits including demonstrated cholesterol-low...
Source: Phytochemistry - Category: Chemistry Source Type: research
Publication date: May 2019Source: American Journal of Kidney Diseases, Volume 73, Issue 5Author(s):
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
Authors: Heijnen NFL, Bergmans DCJJ, Schnabel RM, Bos LDJ PMID: 30997202 [PubMed]
Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
ConclusionOverall, the results support the notion that quantity of whole egg intake does not affect CVD risk factors and consuming egg substitutes may also be beneficial compared to whole eggs on lowering CVD risk in the middle-aged and older population.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Authors: Kalam MA, Alshehri S, Alshamsan A, Alkholief M, Ali R, Shakeel F Abstract Gemfibrozil (GEM) is cholesterol-lowering agent which is being proposed as poorly water soluble drug (PWSD). Temperature based solubility values of GEM are not yet available in literature or any pharmacopoeia/monograph. Hence, the present studies were carried out to determine the solubility of PWSD GEM (as mole fraction) in various pharmaceutically used solvents such as "water (H2O), methanol (MeOH), ethanol (EtOH), isopropanol (IPA), 1-butanol (1-BuOH), 2-butanol (2-BuOH), ethylene glycol (EG), propylene glycol (PG), polyethyle...
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research
Based on a score diagram established by the European Society for Cardiology (Conroy et al. Eur Heart J 24:987,2003) we determined the 10-year risk for cardiovascular (CV) letality in 85 (32 female, 53 male) psoriasis patients (pts) started on adalimumab treatment. Pts were recruited over 12 months. Gender, age, nicotine use (smoking), systolic blood pressure (SBP) and the ratio of total cholesterol/high density lipoprotein (LDL) cholesterol in blood served to establish the 10-year fatal risk. 39 patients were ≤ 47 years of age and 46 were 48-81 years old.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Epidemiology Source Type: research
7-dehydrocholesterol (7DHC) is a precursor of cholesterol biosynthesis and its pathological accumulation is linked to the photosensitive Smith-Lemli-Opitz syndrome. 7DHC is photoconverted by ultraviolet radiation (UV) in epidermal keratinocytes to pre-Vitamin D3 which isomerizes and is enzymatically hydroxylated to other biologically active forms. Exogenously administered vitamin D3 hydroxylated derivatives in human keratinocytes promote upregulation of XPC, a vital component of nucleotide excision repair pathway, suggesting a compensatory response to DNA damage incurred upon UV exposure during Vitamin D photosynthesis.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Photobiology Source Type: research
Lichen planopilaris (LPP) is a primary lymphocytic scarring alopecia whose incidence and prevalence are poorly defined. The literature reports LPP patients comprise
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Skin, Appendages, and Stem Cell Biology Source Type: research
Frontal Fibrosing Alopecia (FFA) is a lymphocytic cicatricial alopecia that predominantly occurs in post-menopausal women. It is characterized by a band-like loss of hair and follicular ostia of the frontal temporal scalp, and commonly involves bilateral eyebrow loss. Over the last 15 years the incidence of FFA has shown a noticeable, albeit unexplained rise. Current accepted treatment is based on expert opinion and includes steroids, hormone blockers, and hydroxychloroquine. To delineate the transcriptional landscape of FFA, we performed RNAseq on scalp biopsies of 18 FFA patients compared with controls.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Skin, Appendages, and Stem Cell Biology Source Type: research
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