Osler-Weber-Rendu Syndrome in Relation to Dermatology.

Osler-Weber-Rendu Syndrome in Relation to Dermatology. Actas Dermosifiliogr. 2019 Apr 08;: Authors: Orizaga-Y-Quiroga TL, Villarreal-Martínez A, Jaramillo-Moreno G, Ocampo-Candiani J Abstract Osler-Weber-Rendu syndrome, also known as hereditary hemorrhagic telangiectasia, is a rare autosomal dominant disorder with an estimated worldwide prevalence of 1 case per 10,000 population. Its clinical manifestations are the result of arteriovenous malformations characterized by telangiectases that can affect the skin, mucous membranes, and solid organs and cause life-threatening conditions, such as liver disease, systemic emboli, and heart failure. Timely diagnosis is thus essential in order to prevent disease-related complications and offer genetic counseling to families. We review the clinical features of Osler-Weber-Rendu syndrome with a focus on mucocutaneous manifestations and their treatment. PMID: 30975431 [PubMed - as supplied by publisher]
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Authors: Tags: Actas Dermosifiliogr Source Type: research