2 life-saving transplant recipients, 2 views on presumed consent for organ donation

Two New Brunswickers who both received life-saving transplants have different views on proposed Nova Scotia legislation that would require adults to opt out of organ donation if they don't want to be donors when they die.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

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Publication date: Available online 17 April 2019Source: Life SciencesAuthor(s): Jiayu Liang, Yongquan Tang, Zhihong Liu, Xianding Wang, Liangyou Tang, Zijun Zou, Chuan Zhou, Kan Wu, Fuxun Zhang, Fan Zhang, Yiping LuAbstractAimsIncreasing evidence has shown the diagnostic value of miR-155 in organ transplantation. The dysregulation of miR-155 is reported to be associated with development of acute or chronic complications in solid organ transplant recipients. Here, we summarized related evidence to explore the correlation between the dysregulation of miR-155 and various allograft dysfunction in transplant recipients, and ver...
Source: Life Sciences - Category: Biology Source Type: research
This study aims to employ a culture system using allogenic limbal niche cells (LNCs) instead of mouse-derived 3T3 cells as a feeder layer that could relieve postoperative neovascularization. Methods: Rat oral mucosal epithelial cells (OMECs) were co-cultured with rat LNCs or 3T3 cells. Cultivated oral mucosal epithelial cells (COMECs) of different culture systems were identified by hematoxylin and eosin staining and immunocytochemistry. The expression levels of the angiogenesis-related factors were analyzed by RT-qPCR and western blotting/ELISA. Angiogenic potential was reconfirmed by cell viability and tube formation...
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Tags: Cell Mol Biol Lett Source Type: research
In this activity, based on a live symposium held during the 2019 Transplantation and Cellular Therapy (TCT) Meetings of the American Society of Blood and Marrow Transplantation (ASBMT) and the Center for International Blood and Marrow Transplant Research (CIBMTR), experts in hematology-oncology explore new developments related to the changing clinical consensus for managing veno-occlusive disease (VOD)/sinusoidal obstruction syndrome (SOS) as a post-transplant complication. In this program, the panelists will share their views on VOD pathophysiology and proposed revisions to diagnostic and severity grading criteria, while ...
Source: Peerview CME/CE Video Podcast - Internal Medicine International - Category: Internal Medicine Authors: Tags: Science, Medicine Source Type: video
(NEW YORK) — Scientists restored some activity within the brains of pigs that had been slaughtered hours before, raising hopes for some medical advances and questions about the definition of death. The brains could not think or sense anything, researchers stressed. By medical standards “this is not a living brain,” said Nenad Sestan of the Yale School of Medicine, one of the researchers reporting the results Wednesday in the journal Nature. But the work revealed a surprising degree of resilience among cells within a brain that has lost its supply of blood and oxygen, he said. “Cell death in the brai...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized Brain Activity onetime Source Type: news
Publication date: 2019Source: European Journal of Radiology Open, Volume 6Author(s): Eliseo Picchi, Francesca Di Giuliano, Simone Marziali, Silvia Minosse, Valentina Ferrazzoli, Valerio Da Ros, Javid Gaziev, Chiara Adriana Pistolese, Roberto Floris, Francesco GaraciAbstractTo evaluate, by Magnetic Resonance Imaging, if there is a typical pattern or severity of PRES in transplanted children for hemoglobinopathy. Secondary point was to investigate the pattern and severity of PRES in children with thalassemia-THAL and sickle-cell disease-SCD after autologous hematopoietic stem cell transplantation (aHSCT). Finally, we evaluat...
Source: European Journal of Radiology Open - Category: Radiology Source Type: research
Tel Aviv University researchers are hoping this technology could eventually be used to help human patients who need heart transplants.
Source: Science - The Huffington Post - Category: Science Source Type: news
Conditions:   Hematologic Diseases;   Stem Cell Transplantation Intervention:   Other: Blood sample Sponsor:   Centre Hospitalier Universitaire de Besancon Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Interstitial Fibrosis/Tubular Atrophy of Transplanted Kidneys Intervention:   Device: MRE exam Sponsor:   University Hospital, Bordeaux Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Companies are testing the ability of fecal transplants and bacteria-stuffed pills to make checkpoint inhibitors work for more people
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
Authors: Fakhreddine AY, Frenette CT, Konijeti GG Abstract Human cytomegalovirus (CMV) is a ubiquitous Herpesviridae virus with a wide spectrum of pathology in humans. Host immunity is a major determinant of the clinical manifestation of CMV and can vary widely in the gastroenterology and hepatology practice setting. Immunocompetent patients generally develop a benign, self-limited mononucleosis-like syndrome whereas gastrointestinal tissue-invasive disease is more frequently seen in immunocompromised and inflammatory bowel disease patients. Additionally, liver allograft dysfunction is a significant consequence of ...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
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