Extended-release vs. oral naltrexone for alcohol dependence treatment in primary care (XON)
Extended-release naltrexone (XR-NTX, Vivitrol ®) and daily oral naltrexone tablets (O-NTX) are FDA-approved mu opioid receptor antagonist medications for alcohol dependence treatment. Despite the efficacy of O-NTX, non-adherence and poor treatment retention have limited its adoption into primary care. XR-NTX is a once-a-month injectable formul ation that offers a potentially more effective treatment option in reducing alcohol consumption and heavy drinking episodes among persons with alcohol use disorders.
Source: Contemporary Clinical Trials - Category: Radiology Authors: Mia Malone, Ryan McDonald, Alexandria Vittitow, Jenny Chen, Rita Obi, Dan Schatz, Babak Tofighi, Annie Garment, Keith Goldfeld, Heather Gold, Eugene Laska, John Rotrosen, Joshua D. Lee Source Type: research