Resection margins obtained with patient-specific instruments for resecting primary pelvic bone sarcomas: A case-control study

The objectives of this case-control study were to determine whether PSI-guided resection: 1) was associated with a lower local recurrence rate, 2) allowed a shorter operative time, 3) was associated with better-quality allograft reconstruction.HypothesisPSI-guided resection decreases the local recurrence rate by improving the resection margins in patients with primary pelvic bone sarcomas.Patients and methodsPSI-guided resection was performed in 9 consecutive patients (cases) with primary pelvic sarcomas (chondrosarcoma, n = 3; Ewing's sarcoma, n = 3; osteosarcoma, n = 1; fibrosarcoma, n = 1; and radiation-induced sarcoma, n = 1). Age ranged from 11 to 63 years. Outcomes were compared to those in a historical control group of 19 patients with primary bone sarcomas who underwent resection surgery in the same hospital without PSI guidance. The case and control groups were similar regarding age, sex distribution, and follow-up duration. The local recurrence rate and operative time were compared between the two groups. Resection margins were classified as R0, R1, or R2. The quality of allograft reconstruction, which was performed in 7 of the 9 cases, was assessed.ResultsAfter a mean follow-up of 52 months (range, 30–90 months), none of the cases had experienced local bone or soft-tissue recurrences, compared to 7 of the 19 controls (p = 0.03), in whom mean follow-up was 62 months (range, 24–134 months). Bone resectio...
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research