Can the Microbiome Deliver? A Proof-of-Concept Engineered E.  coli PKU Therapeutic.

Can the Microbiome Deliver? A Proof-of-Concept Engineered E. coli PKU Therapeutic.
Cell Host Microbe. 2019 Apr 10;25(4):473-474
Authors: Alteri CJ
Abstract
Phenylketonuria (PKU) is a rare genetic disorder that causes phenylalanine toxicity in the brain. Two studies, Crook et al. (2019), in this issue of Cell Host & Microbe, and Isabella et al. (2018), employ synthetic biology to develop a live bacterial therapeutic to treat PKU and potentially other metabolic diseases.
PMID: 30974078 [PubMed - in process]

Source: Cell Host and Microbe - April 9, 2019 Category: Microbiology Authors: Alteri CJ Tags: Cell Host Microbe Source Type: research