Exploitation of the Escherichia coli lac operon promoter for controlled recombinant protein production.

Exploitation of the Escherichia coli lac operon promoter for controlled recombinant protein production. Biochem Soc Trans. 2019 Apr 10;: Authors: Browning DF, Godfrey RE, Richards KL, Robinson C, Busby SJW Abstract The Escherichia coli lac operon promoter is widely used as a tool to control recombinant protein production in bacteria. Here, we give a brief review of how it functions, how it is regulated, and how, based on this knowledge, a suite of lac promoter derivatives has been developed to give a controlled expression that is suitable for diverse biotechnology applications. PMID: 30971435 [PubMed - as supplied by publisher]
Source: Biochemical Society Transactions - Category: Biochemistry Authors: Tags: Biochem Soc Trans Source Type: research