Corrigendum: Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen

Corrigendum: Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen Joe Abdo1, Christopher S. Wichman2, Nicholas E. Dietz1,3, Pawel Ciborowski4, John Fleegel1, Sumeet K. Mittal1,5 and Devendra K. Agrawal1* 1Department of Clinical and Translational Science, Creighton University School of Medicine, Omaha, NE, United States 2Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States 3Department of Pathology, CHI Health Creighton University Medical Center, College of Medicine, Omaha, NE, United States 4Department of Pharmacology, University of Nebraska Medical Center, Omaha, NE, United States 5Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Dignity Health, Phoenix, AZ, United States A Corrigendum on Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen by Abdo, J., Wichman, C. S., Dietz, N. E., Ciborowski, P., Fleegel, J., Mittal, S. K., et al. (2018). Front. Oncol. 8:157. doi: 10.3389/fonc.2018.00157 In the original article, there was a mistake in Figure 2 and Figure 3 as published. The tissue sample N's were reported as (Normal = 20, Barrett's = 10, Tumor = 20), the actual N's analyzed were (Normal = 20, Barrett's = 7, Tumor = 18). The units for the mass spec quantification data in the Figure 2 and Figure 3 were liste...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research

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ConclusionHCV core and IL-22 and SOCS-3 molecules are found to be correlated statistically under this study. Concluded from this study that HCV core protein plays a potential role in diverging the hepatocytes from normal to carcinogenic. One cell signaling path cannot decide, the direct role of a single viral protein in developing viral induced hepatocarcinogenesis. Interpreting the complex network of cell signaling involved in HCC development is impractical to study under single study. That is why step by step unmasking the interactive role of few molecules under single study is the ideal way to resolve the impact of vira...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
In this study, we found that Lnc-OC1 was significantly higher in PCOS granulosa cells (GCs) compared to non-PCOS GCs. Lnc-OC1 knockdown inhibited cell viability and promoted cell apoptosis, expression of aromatase mRNA and production of estradiol in KGN cells. In PCOS mice, Lnc-OC1 promoted the serum insulin release, production of angiogenesis-related factors and IκBα phosphorylation, which could be partially restored by Lnc-OC1 shRNA. These results suggest that Lnc-OC1 plays an important part in the pathogenesis of PCOS.
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 15 February 2020Source: Pharmacological ResearchAuthor(s): Yuanlin Wu, Jing Li, Parham Jabbarzadeh Kaboli, Jing Shen, Xu Wu, Yueshui Zhao, Huijiao Ji, Fukuan Du, Yejiang Zhou, Yongzhou Wang, Hanyu Zhang, Jianhua Yin, Qinglian Wen, Chi Hin Cho, Mingxing Li, Zhangang XiaoAbstractNatural killer (NK) cells are immune cells which are able to kill tumor and virus-infected cells and play an important role in both innate immunity and acquired immunity. Tumor immunotherapy is an emerging model of tumor treatment in the clinic. It is a re-emerging type of anticancer immunotherapy with the purpose o...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 15 February 2020Source: Seminars in Cancer BiologyAuthor(s): Cristina Florean, Mario Dicato, Marc DiederichAbstractThe recent advances in cancer immunotherapy confirm the crucial role of the immune system in cancer progression and treatment. Chronic inflammation and reduced immune surveillance are both features of the tumor microenvironment. Strategies aimed at reverting pro-tumor inflammation and stimulating the antitumor immune components are being actively searched, and the anticancer effects of many candidate drugs have been linked to their ability to modulate the immune system. Marin...
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research
Publication date: Available online 15 February 2020Source: Trends in Anaesthesia and Critical CareAuthor(s): Sima Patel, Andrea Estevez, Nicholas Nedeff, Jose Gascon, Ilde LeeAbstractAcross the United States (U.S.), very few centers exist with an intensive care unit (ICU) solely dedicated to obstetrics (OB) and gynecology (GYN) patients. The management of obstetric patients, who are admitted to a general intensive care unit, can often be accompanied by a fair share of apprehension owing to the intricacy of care. Rather than discussing common obstetric emergencies and their management, we would like to call attention to bas...
Source: Trends in Anaesthesia and Critical Care - Category: Anesthesiology Source Type: research
ConclusionsThe variability of radiocholine uptake in adrenal glands depends probably on overall body metabolism and hypophyseal function expressed by statistically significant correlation with liver and pituitary gland uptake.Predominant focal or mixed with focal areas uptake patterns on positron emission tomography in normal in computed tomography adrenal glands should be assessed with caution to avoid a diagnostic mistake.
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Authors: Meyer D, Smit DP Abstract Both infective and neoplastic eyelid and orbital conditions in human immunodeficiency virus (HIV) infected patients are often the result of opportunistic or co-infections (OI). In most cases, these clinical findings in younger patients alert the physician to suspected underlying HIV infection. When the eyelids and periorbital skin are primarily involved in OI with varicella-zoster virus it is called Herpes Zoster Ophthalmicus. Co-infection with a Pox virus manifests as molluscum contagiosum eruptions. Orbital cellulitis is secondary to various organisms (Mycobacterium tuberculosis...
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
CONCLUSION: [18F]TFB was shown to be a promising hNIS-substrate in our model using the human MCF-7 breast cancer cell line mandating in vivo evaluations in xenografted studies and in patients. PMID: 32056515 [PubMed - in process]
Source: Current Cancer Drug Targets - Category: Cancer & Oncology Authors: Tags: Curr Cancer Drug Targets Source Type: research
Publication date: Available online 16 February 2020Source: Materials Today: ProceedingsAuthor(s): C. Venkata Siva Rama Prasad, T.V.S. Vara LakshmiAbstractThe healing proportion of strengthening cracks in buildings such as Reinforced cement concrete (RCC) Houses, RCC Pipes, Canal Lining, Pavement etc. has been increased in the ongoing bacterial concrete. In order to fix the cracks in the concrete, it needs ordinary maintenance and exceptional treatment that can be terribly expensive. This is another method adopted by the use of microbiologically actuated calcite (CaCO3) precipitation in the arrangement of concrete. In this ...
Source: Materials Today: Proceedings - Category: Materials Science Source Type: research
Publication date: Available online 16 February 2020Source: Materials Science and Engineering: CAuthor(s): Witta Kartika Restu, Shota Yamamoto, Yuki Nishida, Hirotoshi Ienaga, Takashi Aoi, Tatsuo MaruyamaAbstractThe present study reports that a short oligopeptide D-P1, consisting of only five D-amino acids, self-assembled into entangled nanofibers to form a hydrogel that functioned as a scaffold for cell cultures. D-P1 (Ac-D-Phe-D-Phe-D-Phe-Gly-D-Lys) gelated aqueous buffer solution and water at a minimum gelation concentration of 0.5 wt%. The circular dichroism (CD) measurements demonstrated the formation of a β-she...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
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