Corrigendum: Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen

Corrigendum: Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen Joe Abdo1, Christopher S. Wichman2, Nicholas E. Dietz1,3, Pawel Ciborowski4, John Fleegel1, Sumeet K. Mittal1,5 and Devendra K. Agrawal1* 1Department of Clinical and Translational Science, Creighton University School of Medicine, Omaha, NE, United States 2Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, United States 3Department of Pathology, CHI Health Creighton University Medical Center, College of Medicine, Omaha, NE, United States 4Department of Pharmacology, University of Nebraska Medical Center, Omaha, NE, United States 5Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Dignity Health, Phoenix, AZ, United States A Corrigendum on Discovery of Novel and Clinically Relevant Markers in Formalin-Fixed Paraffin-Embedded Esophageal Cancer Specimen by Abdo, J., Wichman, C. S., Dietz, N. E., Ciborowski, P., Fleegel, J., Mittal, S. K., et al. (2018). Front. Oncol. 8:157. doi: 10.3389/fonc.2018.00157 In the original article, there was a mistake in Figure 2 and Figure 3 as published. The tissue sample N's were reported as (Normal = 20, Barrett's = 10, Tumor = 20), the actual N's analyzed were (Normal = 20, Barrett's = 7, Tumor = 18). The units for the mass spec quantification data in the Figure 2 and Figure 3 were liste...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research

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Publication date: Available online 24 May 2019Source: Veterinary MicrobiologyAuthor(s): Sante Roperto, Valeria Russo, Francesca De Falco, Alessandra Rosati, Cornel Catoi, Franco RopertoAbstractE5 protein, the major oncoprotein of the bovine Deltapapillomavirus genus, has been detected in 17 of the 19 urothelial cancers by molecular and morphological procedures. In 10 urothelial cancers, the oxygen sensitive subunit HIF-1α, which is upregulated by hypoxia, was overexpressed. Mitophagy, the selective autophagic removal of dysfunctional mitochondria, was upregulated in hypoxic neoplastic cells infected by BPVs which was...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
Conclusion: Formal consensus was achieved for the first time on a core list of knowledge items on how exercises and physical activities might stimulate anticancer immunity. This core list might be considered at the time of developing training/educational interventions and/or continuing education for primary healthcare providers and CAM practitioners. Future studies are still needed to investigate if such consensual lists might improve congruence in cancer care continuum and improve survival rates and wellbeing of cancer patients and survivors. PMID: 31118968 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Authors: Oei SL, Thronicke A, Schad F Abstract In early tumor development, cancer cells develop a plethora of strategies to escape surveillance from the adaptive and innate immune system. Cancer immunotherapies, in particular immune checkpoint inhibitors, are becoming a highly promising cancer therapeutic approach that has remarkable increased progress in combating various cancer types. Unfortunately, their mechanisms of action induce some complications, such as inflammatory reactions and immune-related adverse events. In the management of side effects during anticancer therapy, complementary and integrative therap...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
Publication date: Available online 25 May 2019Source: Biosensors and BioelectronicsAuthor(s): Shao Su, Qian Sun, Ling Wan, Xiaodan Gu, Dan Zhu, Yi Zhou, Jie Chao, Lianhui WangAbstractUltrasensitive detection of cancer biomarkers has shown great promise for precision medicine. Here, a triple signal amplification strategy was developed for analysis of carcinoembryonic antigen (CEA) by using MoS2-based nanocomposites. Gold nanoparticles-decorated molybdenum disulfide nanocomposite (MoS2-AuNPs) was used to construct the modified electrode and nanoprobe, which could efficiently amplify electrochemical signal due to its large su...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 24 May 2019Source: Molecular Aspects of MedicineAuthor(s): Ester Saus, Susana Iraola-Guzmán, Jesse R. Willis, Anna Brunet-Vega, Toni GabaldónAbstractThe gastrointestinal tract harbors most of the microbiota associated with humans. In recent years, there has been a surge of interest in assessing the relationships between the gut microbiota and several gut alterations, including colorectal cancer. Changes in the gut microbiota in patients suffering colorectal cancer suggest a possible role of host-microbe interactions in the origin and development of this malignancy and, at th...
Source: Molecular Aspects of Medicine - Category: Molecular Biology Source Type: research
Publication date: Available online 24 May 2019Source: Fish &Shellfish ImmunologyAuthor(s): Xiaobing Liu, Xuemei Li, Meiting Peng, Xuangang Wang, Xinxin Du, Lihui Meng, Jieming Zhai, Jinxiang Liu, Haiyang Yu, Quanqi ZhangAbstractC-type lectin is a type of carbohydrate-binding protein and plays significant roles in innate immune response against pathogen infection. To date, thousands of C-type lectin had been identified in teleost. In the present study, we isolated a novel isoform of C-type lectin (OppCTL) from spotted knifejaw (Oplegnathus punctatus). The OppCTL encoded a typical Ca2+-dependent carbohydrate-binding prot...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 25 May 2019Source: Chemico-Biological InteractionsAuthor(s): Yingzhuan Zhan, Nan Ma, Rui Liu, Nan Wang, Tao Zhang, Langchong HeAbstractPolymyxin B (PMB) and polymyxin E (PME) are cyclic, peptide antibiotics which derived from various species of Paenibacillus (Bacillus) polymyxa. They are decapeptide antibiotics with an antimicrobial spectrum that includes Gram-negative bacteria, and reused as therapeutic agents due to the emergence of multidrug-resistant (MDR) Gram-positive bacteria. PMB or PME-induced anaphylactoid reactions in the clinic have been documented. However, the mechanism unde...
Source: Chemico Biological Interactions - Category: Biochemistry Source Type: research
In this study, based on the phase transition of Ca4Al6SO16 from the low-temperature orthorhombic phase (o-Ca4Al6SO16) to high-temperature cubic phase (c-Ca4Al6SO16), the existent impurity phase in o-Ca4Al6SO16 with excess addition of CaSO4 is verified as Ca3Al2O6 rather than Ca12Al14O33 with the closest Ca/Al ratio to the main phase. Meanwhile, the Eu3+ fluorescence prober shows a more sensitive detection capability than x-ray powder diffraction, especially when the content of Ca3Al2O6 below 2 wt. %. By virtue of the different crystal-field splittings of Eu3+ ions in o-Ca4Al6SO16 and Ca3Al2O6, the near-pure o-Ca4Al6...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Soft Matter, 2019, Accepted Manuscript DOI: 10.1039/C9SM00526A, PaperMatteo Campo, Simon Kaspar Schnyder, John Jairo Molina, Thomas Speck, Ryoichi Yamamoto The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Preliminary Proposal Deadline Date: June 24, 2019 Program Guidelines: NSF 19-517The Materials Research Science and Engineering Centers (MRSECs) program provides sustained support of interdisciplinary materials research and education of the highest quality while addressing fundamental problems in science and engineering. Each MRSEC addresses research of a scope and complexity requiring the scale, synergy, and multidisciplinarity provided by a campus-based research center. The MRSECs support materials research infrastructure in the United States, promote active ...More at https://www.nsf.gov/funding/pgm_summ.jsp?pims_id=5295...
Source: NSF Upcoming Due Dates - Category: Science Source Type: funding
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