Complications of measles
Since it is not a brief answer, rather than respond to Mr. Bachtell's question in the comments, I'll do a front page post on it.CDC provides information about complications of measles here. This applies to the United States and other wealthy countries. Measles is much more dangerous in poor countries where many children are malnourished or debilitated from chronic infections, but that's a bit off topic.The actual death rate from measles in developed countries is about 1-2 per 1,000. However, 1 in 20 children will get pneumonia as a complication, which may require expensive treatment including mechanical ventilation. An additional 1 child in 1,000 will develop encephalitis which may lead to permanent brain damage. A rarer complication issubacute sclerosing panencephalitis which develops several years after a measles infection. It is a progressive, disabling, fatal brain disorder which occurs in something like 4-11 out of 100,000 cases of measles but may be more common in children under 2 years of age.The National Health Service lists additional complications including damage to vision and hepatitis. Measles in pregnant women increases risk of miscarriage, stillbirth, and premature delivery. We have not had the experience of a widespread measles epidemic in the present era in which there are more immunocompromised people in the population due to modern treatment of autoimmune disorders, transplant surgery, and HIV. These vulnerable people are at particular risk from those who r...
Authors: Takada S, Saito MK, Kambe N Abstract Blau syndrome, or early-onset sarcoidosis, is hereditary juvenile-onset systemic granulomatosis. Clinical symptoms appear before the age of 4 years and mainly affect the skin, joints, and eyes. The symptoms are progressive and cause severe complications, such as joint destruction and blindness. Although tumor necrosis factor alpha (TNFα) antagonists are effective for controlling some of the symptoms of Blau syndrome, there is no specific curative treatment. Heterozygous mutations in nucleotide-binding oligomerization domain 2 (NOD2) were identified as the cause of...
Publication date: Available online 3 July 2020Source: Saudi Journal of Biological SciencesAuthor(s): Shafat Ali, Sabhiya Majid, Md. Niamat Ali, Shahnaz Taing, Hamed A. El-Serehy, Fahad A. Al-Misned
Publication date: 4 July 2020Source: New Scientist, Volume 247, Issue 3289Author(s): Jessica Hamzelou
Publication date: Available online 3 July 2020Source: Spatial and Spatio-temporal EpidemiologyAuthor(s): Felix Tran, Christopher Morrison
Abstract Major depressive disorder (MDD) is a debilitating illness with significant morbidity and mortality, leading to attempted and completed suicides. It affects interpersonal relationships and also contributes to decreased productivity, causing financial burden to individuals and society. Patients often fail to respond to various antidepressant medication trials resulting in treatment-resistant depression (TRD). Current antidepressant medications work by modulating the monoaminergic systems and takes several weeks to establish a clinical response. Ketamine has been used extensively as an anesthetic agent since...
Publication date: Available online 9 June 2020Source: Safety and Health at WorkAuthor(s): BongKyoo Choi
Publication date: October 2020Source: Preventive Medicine, Volume 139Author(s): Terri Flood, Iseult M. Wilson, Gillian Prue, Marian McLaughlin, Ciara M. Hughes
ConclusionsHaploidentical HSCT may be a treatment option for patients with XIAP deficiency who lack a good matched donor. More studies are needed to determine whether modified MAC with reduced toxicity is more suitable for haploidentical transplantation.
Authors: Amo-Lozano A, Portilla-Tamarit J, Portilla J PMID: 32616316 [PubMed - as supplied by publisher]
Publication date: Available online 3 July 2020Source: Respiratory InvestigationAuthor(s): Takahiro Takazono, Yoshifumi Imamura, Kaoru Kawakami, Naoya Yamasaki, Hiroyoshi Shimizu, Katsuhiro Usuki, Maiko Kiyohara, Tatsuro Hirayama, Masato Tashiro, Naoki Hosogaya, Tomomi Saijo, Kazuko Yamamoto, Taiga Miyazaki, Katsunori Yanagihara, Koichi Izumikawa, Hiroshi Mukae
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