Two Sides of the Same Coin: A Case Report of First-Episode Catatonic Syndrome in a High-Functioning Autism Patient

Conclusion: This case represents an example of diagnostic and therapeutic challenges of catatonic schizophrenia in high-functioning autism due to clinical and neurobiological overlaps of these conditions. We discuss clinical features together with pathophysiological concepts of both conditions. Furthermore, we tackle social and legal hurdles in Germany that naturally arise in these patients. Finally, we present diagnostic “red flags” that can be used to rationally select and conduct current recommended diagnostic assessments if there is a suspicion of ASD in patients with catatonic syndrome in order to provide them with the most appropriate treatment.BackgroundSchizophrenia and autism spectrum disorders (ASD) are common, highly heritable, and severe neurodevelopmental disorders with overlapping genetic, neurobiological, and clinical characteristics. Schizophrenia is a complex brain disorder with an average prevalence of about 0.6% (1). ASD are classified as pervasive developmental disorders in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) with an estimated prevalence of 0.6–1% in the general population (2). The core symptoms of ASD are impairments in social interaction, impairments in communication, and restricted as well as repetitive behaviors (3). ASD are usually diagnosed in childhood or adolescence. If the patient exhibits flamboyant psychotic and catatonic symptoms, clinicians are confronted with considerable difficul...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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Source: Anxiety, Stress and Coping - Category: Psychiatry & Psychology Authors: Source Type: research
Publication date: Available online 21 January 2020Source: Advances in Space ResearchAuthor(s): Zhenghai Wang, Cong Zhou, Haoyang QinAbstractAdvanced space-borne thermal emission and reflection radiometer (ASTER) data were evaluated for the hydrothermal alteration mapping of the Nimu porphyry copper deposit, southern Tibet. According to the metallogenic model for porphyry copper, we chose hydrothermal alteration mineral association and then established a remote sensing model. Relative absorption-band depth (RBD) and simple band combination methods in visible near infrared (VNIR) and shortwave infrared (SWIR) bands were used...
Source: Advances in Space Research - Category: Science Source Type: research
AbstractGlioblastoma is a devastating tumor affecting the central nervous system with infiltrative capacity, high proliferation rate and chemoresistance. Therefore, it is urgent to find new therapeutic alternatives that improve this prognosis. Herein, we focused on tannic acid (TA) a polyphenol with antioxidant and antiproliferative activities. In this work, the antitumor and antioxidant effects of TA on rat (C6) glioblastoma cells and their cytotoxicity relative to primary astrocyte cultures were evaluated in vitro. Cells were exposed to TA of 6.25 to 75  μM for 24, 48 and/or 72 h. In addition, colony formati...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
[USAID] On December 27 and December 31, 2019, the U.S Agency for International Development (USAID) launched the first two in a series of global health awards to accelerate reductions in maternal, newborn, and child mortality and morbidity in high-burden countries.
Source: AllAfrica News: Pregnancy and Childbirth - Category: OBGYN Source Type: news
Abbott Laboratories has been wildly successful with its FreeStyle Libre continuous glucose monitor (CGM) since winning FDA approval in 2017, but it seems some investors and patients may be getting restless as the U.S. market waits for the second-generation of the blockbuster technology. We first noted some signs of impatience for Libre 2 in our coverage of Abbott's third-quarter earnings call in October. One reader commented on that article that "I don’t particularly care about investors becoming impatient, as a Freestyle Libre user I am growing impatie...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
Publication date: Available online 21 January 2020Source: Hematology/Oncology Clinics of North AmericaAuthor(s): Norbert Gattermann
Source: Hematology Oncology Clinics of North America - Category: Hematology Source Type: research
Authors: Monsalve Alonso S, Miranda García P, Santander Vaquero C Abstract Cap-polyposis is a rare benign condition characterized by inflammatory colorectal polyps covered by a "cap" of fibrinopurulent exudate. Mucous diarrhea and rectal bleeding are frequent symtoms. It can be difficult to diagnose and it is necessary to make a differential diagnosis from other entities. Its pathogenesis is unknown and it has a variable clinical course. The optimal treatment has not been established. PMID: 31960689 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
We present the case of a 74-year-old man, with a history of residual schizophrenia, who underwent abdominal-pelvic CT with intravenous contrast, due to abdominal acute pain, that showed a stenosis at the origin of the celiac trunk and a large aneurysm of the hepatic artery, secondary to a mediam arcuate ligament syndrome, of the diaphragm was observed. PMID: 31960685 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
We report the case of a 60-year-old male with a giant colorectal laterally spreading tumor at the recto-sigmoid junction. A single tunnel-assisted endoscopic submucosal dissection was performed that constructed a submucosal tunnel along the longitude axis of the tumor. An en bloc resection was achieved with no perforation or post-operative bleeding and a comparatively low procedure time. PMID: 31960681 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
Authors: Ruiz Rebollo ML, González Obeso E, Burgueño Gómez B, Santos Fernández J Abstract A 75-year-old male was referred due to dysphagia and iron-deficiency anemia. An upper endoscopy was performed which revealed a friable mass at 30 to 37 cm from the incisors, consistent with esophageal malignancy. However, the pathology only demonstrated granulation inflammatory tissue. An endoscopic ultrasound exam showed a 2-3 cm esophageal wall thickening with a 1.5 cm lymph node, which was staged as a T2-3 N1 esophageal tumor. A CT-scan also identified a 7.5 cm esophageal malignancy surrounded by...
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
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