Altered Local and Large-Scale Dynamic Functional Connectivity Variability in Posttraumatic Stress Disorder: A Resting-State fMRI Study

In conclusion, this resting-state dFC (combine the dReHo and dFC) study provided evidence that the PTSD patients exhibited aberrant dReHo and dFC in comparison with the HC. Decreased variability within the DMN may suggest dysfunction of self-referential processing in PTSD patients, while increased variability between the insula and PCu may suggest dysregulation between the DMN and the SN.Ethics StatementPermission to undertake this study was granted by the ethics committee of Guangdong Second Provincial General Hospital.Author ContributionsSF designed the experiment. SF and XM carried out the experiment. ZB collected and sorted out the data. YW, MLiu, YY, ZL, SH, MLi, and KH helped on data management and processing. SF and GJ wrote the manuscript.Conflict of Interest StatementThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.Supplementary MaterialThe Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpsyt.2019.00234/full#supplementary-materialReferences 1. Yehuda R, Hoge CW, McFarlane AC, Vermetten E, Lanius RA, Nievergelt CM, et al. Post-traumatic stress disorder. Nat Rev Dis Primers (2015) 1:15057. doi: 10.1038/nrdp.2015.57PubMed Abstract | CrossRef Full Text | Google Scholar 2. YaŞan A, Güzel A, Tamam Y, Ozkan M. Predictive factors for acute stress disorder and posttraumatic stress di...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research