CDC: Superbug Fungus Has Sickened 600 Americans

THURSDAY, April 11, 2019 -- The United States has had more than 600 cases of infection with a type of fungus called a " serious global health threat " by the U.S. Centers for Disease Control and Prevention. The first U.S. cases of Candida auris...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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In this study, we report a series of cationic peptidopolysaccharides synthesized by thiol-ene click chemistry of grafting antimicrobial polypeptides, methacrylate-ended poly(lysine-random-phenylalanine) (Me-KnFm), onto a thiolated polysaccharide (Dextran, Dex) backbone. Their copolymers (Dex-g-KnFm) exhibit potent broad-spectrum antibacterial and antifungal activity against Gram-negative bacteria (Pseudomonas aeruginosa and Escherichia coli), Gram-positive bacteria (methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus epidermidis) and fungi (Candida albicans) with minimal inhibitory concentrations at a ran...
Source: Biomacromolecules - Category: Biochemistry Authors: Tags: Biomacromolecules Source Type: research
I have to admit it: recent news reports about a newly described “superbug” are worrisome and at least a little bit terrifying. This time, it’s not a flesh-eating bacterium or drug-resistant tuberculosis — in fact, it’s not a bacterial infection at all. It’s a fungus called Candida auris (C. auris). If the first part of the name sounds familiar, that may be because other Candida species (such as Candida albicans, glabrata, and tropicalis) cause common vaginal and skin infections. They’re often called yeast infections and while quite bothersome, they only rarely cause serious illness...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Health trends Infectious diseases Men's Health Women's Health Source Type: blogs
Infection with either mobilized colistin resistance-1 gene–positive gram-negative bacteria or invasive Candida lusitaniae occurs rarely throughout the United States. Here we report the existence of both invasive infections occurring in a single, complex patient who initially presented with necrotizing pancreatitis and gastrointestinal bleeding. We detail the patient’s history and perioperative course for enterocutaneous fistulae takedown and ureteral stenting, describe a template of preventative steps taken in the perioperative environment to prevent nosocomial pathogen transmission, and provide a brief overvie...
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research
In conclusion, potential biological applications of PF-SeNPs were explored by antibacterial, antifungal, antioxidant and biocompatibility assays. Materials and Methods Chemicals and Reagents Sodium selenite (98%), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT), Tween 80, methanol, acetate buffer, tetracycline, nystatin, rhodamine 123, caspase-3 kit, Dulbecco’s modified Eagle media (DMEM), Folin-Ciocalteu reagent, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), Dulbecco’s phosphate buffered saline pH 7.4 (DPBS) and fetal bovine serum (FBS) w...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
What you need to know about an emerging superbug.(Image credit: Nicolas Armer/picture alliance via Getty Images)
Source: NPR Health and Science - Category: Consumer Health News Source Type: news
Stephanie Spoor, who first fell ill in November, died on February 11 in Chicago, days after one of her sons Zack married his fiancee Carley at her bedside in hospital gowns. She had contracted Candida auris.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Natural News) Candida auris is a “silent superbug” that’s already spreading across U.S. hospitals and nursing homes. The CDC has reported hundreds of infections across seven states, and is tracking over 1,000 “colonizations” where the fungal strain has infected human carriers who spread it to others. Notably, the CDC refuses to name which hospitals have...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Conclusion: The River Nile could be a new source for production of promising bioactive leading compound where antimicrobial and antiparasitic activities may be correlated. Introduction Nature is an exceptional resource of new biologically active compounds with an astonishing chemical diversity such as that found in plant species, animals, and microorganisms (Butler et al., 2014). Microbial diversity constitutes an infinite pool of novel chemistry, making up a valuable source for innovative biotechnology (Bérdy, 2005; Fenical and Jensen, 2006). The aquatic environment is now becoming more appreciated as a ri...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
It began in 2009, when doctors in Tokyo swabbed the ear of a 70-year-old woman and found an unknown strain of fungus that can infect humans and, in severe cases, cause a blood infection in high-risk patients. It's called Candida auris.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
This study aims to investigate the efficiencies of seven methods in C. albicans biofilm EM extraction, namely vortexing plus ultrasonication (VU), formaldehyde plus vortexing and ultrasonication (Formaldehyde-VU), EDTA plus vortexing and ultrasonication (EDTA-VU), NaOH plus vortexing and ultrasonication (NaOH-VU), ethanol plus vortexing and ultrasonication (Ethanol-VU), ion exchange resin plus vortexing and ultrasonication (IER-VU)—including cation/anion-exchange resin plus vortexing and ultrasonication (CER/AER-VU)—under the static and dynamic states. Subsequently, the extracted metabolites are analyzed with t...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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