A New Jersey High School Principal Died After Donating Bone Marrow to a Young Boy in France

A popular New Jersey high school principal died Sunday after donating bone marrow to a young boy in France, his family confirmed to news outlets. Derrick Nelson, who was the principal at New Jersey’s Westfield High School, never recovered after falling into a monthlong coma following a bone marrow donation procedure at a Bergen County hospital, his father told NJ.com. Nelson died Sunday at age 44, though the exact cause of his death was unclear, his father said; he told ABC News that his son may have had a heart attack. Nelson was donating bone marrow to supply stem cells to a 14-year-old boy in France with an undisclosed illness, he told Westfield’s student newspaper before the procedure. “If it’s just a little bit of pain for a little bit of time that can give someone years of joy, it’s all worth it,” Nelson said during the interview. In that interview, he also said he had sleep apnea and a blood trait related to sickle cell anemia — two conditions that complicated doctors’ plans for the donation procedure. It was unclear from media reports if the donation procedure was ultimately successful. Students and public officials alike are publicly mourning Nelson, who was reportedly engaged to be married and had a six-year-old daughter. In a letter sent to students and parents, according to NJ.com, Westfield School District Superintendent Margaret Dolan wrote that, “Dr. Nelson touched us all with his kindness, compassion, inte...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Education New Jersey onetime Source Type: news

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Authors: Mohiuddin OA, Campbell B, Poche JN, Thomas-Porch C, Hayes DA, Bunnell BA, Gimble JM Abstract Decellularized tissues are gaining popularity as scaffolds for tissue engineering; they allow cell attachment, proliferation, differentiation, and are non-immunogenic. Adipose tissue is an abundant resource that can be decellularized and converted in to a bio-scaffold. Several methods have been developed for adipose tissue decellularization, typically starting with freeze thaw cycles, followed by washes with hypotonic/hypertonic sodium chloride solution, isopropanol, detergent (SDS, SDC and Triton X-100) and trypsi...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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Source: Progress in Biophysics and Molecular Biology - Category: Molecular Biology Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
This study aimed to examine whether (−)-α-bisabolol (BISA), a natural terpene, can attenuate nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain.Materials and methodsInfraorbital nerve transection (IONX) or sham operation was performed in adult male rats. Head withdrawal thresholds as a measure of facial mechanical sensitivity were tested with von Frey monofilaments applied bilaterally to the facial vibrissal pad pre-operatively (baseline) and then post-operatively before and at 60, 120, 240 and 360 min after administration of vehicle control per oris (p.o.) or BIS...
Source: Life Sciences - Category: Biology Source Type: research
Abstract Fisetin (3,3',4',7-tetrahydroxyflavone) is a bioactive polyphenolic flavonoid found in many fruits and vegetables. It exhibits a variety of pharmacological activities including anticancer and anti-invasive effects. Epithelial to mesenchymal transition (EMT) allows the tumor cells to acquire increased migratory and invasive properties mediating their dissemination to faraway sites, thus favoring metastasis. With metastatic lung cancer claiming the majority of lung cancer-related deaths, agents targeting the pathways underlying metastasis are translationally promising. In the present study, we have explored...
Source: Chemico-Biological Interactions - Category: Molecular Biology Authors: Tags: Chem Biol Interact Source Type: research
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Source: International Journal of Food Sciences and Nutrition - Category: Nutrition Tags: Int J Food Sci Nutr Source Type: research
This study aims to employ a culture system using allogenic limbal niche cells (LNCs) instead of mouse-derived 3T3 cells as a feeder layer that could relieve postoperative neovascularization. Methods: Rat oral mucosal epithelial cells (OMECs) were co-cultured with rat LNCs or 3T3 cells. Cultivated oral mucosal epithelial cells (COMECs) of different culture systems were identified by hematoxylin and eosin staining and immunocytochemistry. The expression levels of the angiogenesis-related factors were analyzed by RT-qPCR and western blotting/ELISA. Angiogenic potential was reconfirmed by cell viability and tube formation...
Source: Cellular and Molecular Biology Letters - Category: Biochemistry Authors: Tags: Cell Mol Biol Lett Source Type: research
A Louisville physician is one of 60 people charged by federal officials for illegally prescribing and distributing opioids and other narcotics and for health care fraud. Dr. Christopher Nelson, owner of the now-closed Bluegrass Pain Consultants PLLC, was charged with a Florida compounding pharmacy and its owner in connection with a scheme that involved the payment of alleged kickbacks in return for writing prescriptions for compounded drugs that included controlle d substances. They also were charged…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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Source: Canadian Medical Association Journal - Category: General Medicine Tags: CMAJ Source Type: research
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