We Finally Learned What a Year in Space Did to Astronaut Scott Kelly ’s Body

Traveling in space looks like all kinds of fun, and in a lot of respects, it is—provided you can overlook a few downsides. There’s the loss of muscle mass, for one thing. Then there’s the decalcification of bones and the stress on the heart and the damage to the eyes and the changes in the immune system and the disruption of the genome and an actual shortening of your overall life expectancy. It was, in part, to study all of those biological problems that astronaut Scott Kelly spent 340 days in space from 2015 to 2016 (chronicled in TIME’s Emmy-nominated series A Year in Space). Now, just over three years after his return, the first tranche of studies into Kelly’s off-world marathon has been published in Science. The results are mixed — Kelly fared better than expected on some measures and worse on others. The overall conclusion is less ambiguous: space travel is exceedingly hard on the human body, and we have a lot to learn before we’re ready to start living on the moon or Mars. One of the things that made Kelly an improbably perfect specimen for the year-in-space study was that he has an identical twin brother, Mark Kelly. Both were NASA astronauts, both are generally fit and healthy and both, of course, share the same basic genome. Take two people with identical genetic software and put them in decidedly non-identical surroundings, and then compare them throughout the year and after. At least some of the differences in health will...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized onetime space Year in Space Source Type: news

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In this study, Lactobacillus plantarum (L. plantarum) KLDS1.0318 preserved in our laboratory was orally administered to CTX-treated mice to explore its potential effects to attenuate the toxic effects of CTX-induced by modulating intestinal immune response, promoting intestinal integrity and improving metabolic profile. BALB/c mice were randomly divided into six groups including normal control group (NC; non-CTX with sterile saline), model control group (MC; CTX-treated with sterile saline), CTX-treated with L. plantarum KLDS1.0318 (10 mL/kg) groups with three different doses (KLDS1.0318-L, 5 × 107 CFU/mL; KLDS1.0318...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
WIRED Health, now in its sixth year, returned to London’s Francis Crick Institute. The event was opened by Crick Institute director Paul Nurse who introduced the institute and its mission to understand the fundamental biology of human heal...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Medicine Public Health Society Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
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