Medical News Today: Signs and symptoms of MS in women

Multiple sclerosis (MS) is a disease that damages the nerves and causes a wide range of symptoms, including vision problems and numbness. In this article, learn about the symptoms of MS in women.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Multiple Sclerosis Source Type: news

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Publication date: Available online 17 April 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Akihiko Mitsutake, Tatsuya Sato, Junko Katsumata, Fumiko Kusunoki Nakamoto, Tomonari Seki, Risa Maekawa, Takuto Hideyama, Jun Shimizu, Yasushi ShiioAbstractTumefactive demyelinating lesions (TDLs) are rare in multiple sclerosis (MS). We herein report a case of tumefactive MS which initially presented with brainstem encephalitis with a long-term follow-up. The patient had experienced relapse mostly in the brainstem in the first twenty years, and then in the periventricular white matter afterwards. The patient responded...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
ConclusionFatigue in MS is a multifactorial construct, with perceived fatigue and cognitive performance fatigability largely influenced by indirect psychological and cognitive factors. Future studies need to take these influences into account when developing fatigue assessment tools. Further, targeting influential fatigue drivers such as psychological variables may improve the burden of fatigue and quality of life of people with MS.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
ConclusionsWe took a cross-national perspective and found many similarities between three European countries across people with RRMS and PMS. Future provision should accommodate the key requirements identified to engage people with MS in scalable mHealth interventions.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
We report a 39-year old man with WNV infection and LETM. In neurological examination, there was a left periscapular hypotrophy, moderate weakness of left arm, decreased left brachioradialis reflex, tandem instability and gait ataxia. Cervical spine MRI showed enhancing intramedullary lesion extending from C3-C7 level. According to the neurological, EMG and MRI findings, a diagnosis of LETM, with affection of anterior horn cells of the cervical spinal cord, induced by WNV infection was established. The patient was treated with antibiotics, acyclovir and high dose-steroids, methylprednisolone (MP) 1g/daily in intravenous inf...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 16 April 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Meng-Ting Cai, Yin-Xi Zhang, Yang Zheng, Wei Fang, Mei-Ping DingAbstractObjective: To clarify the features of callosal lesions on magnetic resonance imaging (MRI) in Multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSD), and acute disseminated encephalomyelitis (ADEM).Methods: Chinese patients diagnosed with MS (n=33), NMOSD (n=31), and ADEM (n=18) were enrolled. Characteristics of lesions in corpus callosum were evaluated with 1.5 Tesla MRI scanners. Chi-squared test (Fisher's exact test) was used ...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 15 April 2019Source: Multiple Sclerosis and Related DisordersAuthor(s): Elena Tsantes, Erica Curti, Ernesto Siena, Franco GranellaAbstractTreatment of MOG Ab-associated disease is poorly standardized: several drugs have been employed, with variable results. A 50-year-old Caucasian male was admitted to hospital in 2009, with severe acute transverse myelitis. A brain and spinal cord MRI showed multiple demyelinating lesions and cerebrospinal fluid analysis revealed no oligoclonal bands (OCBs). A diagnosis of multiple sclerosis (MS) was made. He was treated with interferon-beta 1a, then with...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Abstract Bioluminescent solid-phase sandwich-type microassay was developed to detect multiple sclerosis (MS)-associated autoantibodies in human sera. The assay is based on two different 2'-F-Py RNA aptamers against the target autoantibodies as biospecific elements, and Ca2+-regulated photoprotein obelin as a reporter. The paper describes elaboration of the assay and its application to 91 serum samples from patients with clinically definite MS and 86 ones from individuals healthy in terms of MS. Based on the receiver-operator curve (ROC) analysis, the chosen threshold value as clinical decision limit offers sensiti...
Source: Analytica Chimica Acta - Category: Chemistry Authors: Tags: Anal Chim Acta Source Type: research
This study is the first to investigate brain activation dynamics during the performance of balance- and attention-demanding motor tasks in persons with MS. PMID: 30987505 [PubMed - as supplied by publisher]
Source: Motor Control - Category: Neurology Tags: Motor Control Source Type: research
Conclusion: Clear evidence demonstrates that GBCAs lead to gadolinium deposition in the brain in a dose-dependent manner; however, only linear GBCAs have been associated with gadolinium deposition visualized on MRI. To date, no evidence links gadolinium deposition with any adverse health outcome. Updated medical society guidelines emphasize the importance of an individualized risk-benefit analysis with each administration of GBCAs. PMID: 30983897 [PubMed]
Source: Ochsner Journal - Category: General Medicine Tags: Ochsner J Source Type: research
(University of Edinburgh) Scientists at the University of Edinburgh have uncovered fresh insights into how vitamin D affects the immune system and might influence susceptibility to diseases such as multiple sclerosis.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
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