Class action proposed over alleged misuse of labour-inducing drug at Moncton Hospital

A proposed class-action lawsuit has been launched against the Horizon Health Network and nurse Nicole Ruest on behalf of women who were allegedly "inappropriately" given a labour-inducing drug at Moncton Hospital.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/New Brunswick Source Type: news

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miR‑199a‑3p suppresses cervical epithelial cell inflammation by inhibiting the HMGB1/TLR4/NF‑κB pathway in preterm birth. Mol Med Rep. 2020 May 22;: Authors: Peng J, Jiang J, Wang H, Feng X, Dong X Abstract Preterm birth (PTB) is the primary cause of neonatal mortality worldwide. Infection and inflammation are considered to be the primary causes of PTB. Cervical remodeling is an important step in the process of preterm delivery, and the destruction of the cervical epithelial barrier and inflammation are important triggers of cervical remodeling. The aim of the present study was to determine...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusion: Though small SCH can be found in quite a few pregnant women and is usually harmless, enormous hematoma can result in adverse pregnancy outcomes. It may be difficult, in some cases, to differentiate it from uterine tumors or placental tumors by means of ultrasonography and magnetic resonance imaging, especially when the mass is hyperechoic under ultrasonography. This case report stresses the importance of regular examinations of pregnant women.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
CONCLUSION: Prior cesarean delivery is correlated with earlier delivery and increased neonatal morbidity. Advocating trial of labor after cesarean delivery may provide maternal and neonatal benefit. PMID: 32459429 [PubMed - in process]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Induction of labor (IoL) is an increasingly common obstetric procedure. Foley catheter IoL is recommended by WHO. It is associated with the lowest rate of uterine hyperstimulation syndrome and similar duration...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
In August 2018, Grobman et  al1 published findings from the ARRIVE Trial: A Randomized Trial of Induction vs Expectant Management. More than 6000 women underwent random assignment at 41 academic and community hospitals that were participating in the Maternal-Fetal Medicine Units Network; 3062 women were assigned to labor ind uction, and 3044 women were assigned to expectant treatment. There was no difference in the primary outcome, which was a composite of adverse perinatal outcomes. Women who underwent labor induction were significantly less likely to deliver by cesarean (18.6 % vs 22.2%; relative risk, 0.84; 95% con...
Source: American Journal of Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Editorial Source Type: research
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
DiscussionUnderstanding predictors of conversion from inhaled N2O to neuraxial analgesia may assist perinatal care providers in their discussions with women about analgesia options during labor. N2O is a useful, safe option for labor analgesia in the United States.
Source: Journal of Midwifery and Women's Health - Category: Midwifery Authors: Tags: Original Research Source Type: research
Publication date: Available online 12 May 2020Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Lisa D. Levine, Catalina M. Valencia, Jorge E. Tolosa
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
The fetal membranes are equipped with high capacity of cortisol regeneration through the reductase activity of 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1). The expression of 11β-HSD1 in the fetal membranes is under the feedforward induction by cortisol, which is potentiated by proinflammatory cytokines. As a result, the abundance of 11β-HSD1 increases with gestational age and furthermore at parturition with an escalation of cortisol concentration in the fetal membranes. Accumulated cortisol takes parts in a number of crucial events pertinent to the onset of labor in the fetal membranes, including extr...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
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