Men who take a drug to tackle prostate disease are a THIRD more at risk of type 2 diabetes  

A study by the University of Edinburgh found men with enlarged prostates who are prescribed drugs called 5-alpha-reductase inhibitors to make urination easier are more at risk of the condition.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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This study aimed to evaluate the therapeutic effect of folic acid (FA) on diabetic retinopathy (DR) in a genetic mouse model of obese type 2 diabetes mellitus (T2D). C57BL/KsJ-db/db(db/db) T2D mice were divided into control, FA, metformin (MET), and FA plus MET groups (n = 10/group). Serum levels of glucose, glycated hemoglobin, and insulin were determined weekly. The retinal thickness was measured using optical coherence tomography (OCT) at 4 weeks after treatments. The retinal expression and serum levels of vascular formation, inflammation, and oxidative stress-associated molecules were examined. Our results demonstrated...
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Conclusions: Eyes from diabetic patients in the initial stages of DR with different Early Treatment Diabetic Retinopathy Study gradings show similar prevalence of SCME and CIME, independent of the severity of the retinopathy. Retinal edema is located mainly in the INL and appears to be mostly extracellular except in the earliest stages of diabetic retinal disease where intracellular edema predominates.Ophthalmic Res
Source: Ophthalmic Research - Category: Opthalmology Source Type: research
Publication date: June 2019Source: Journal of Functional Foods, Volume 57Author(s): Kamesh Venkatakrishnan, Hui-Fang Chiu, Chin-Kun WangAbstractDiabetes mellitus (DM) and its related complications are the serious public health concern globally. This is the first review highlight on major functional foods and herbs with anti-diabetic activity particularly focus on type 2 diabetes mellitus (T2DM) with special reference to clinical trials and their proposed anti-diabetic mechanisms. This contribution summarizes the current prevalence of DM, etiology and pathophysiology, complications related to DM, current conventional treatm...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
This study briefly reviews the physiological mechanisms of exercise therapy in diabetes and the potential role of these cytokines in exercise.Key Messages: More high-quality, targeted, randomized controlled studies are needed urgently, from mechanism study to treatment direction, to provide a more theoretical basis for exercise therapy and to explore new therapeutic targets for diabetes.Ann Nutr Metab 2019;74:313 –321
Source: Annals of Nutrition and Metabolism - Category: Nutrition Source Type: research
Platelet (PLT) hyperactivity is a key factor which contributes to cardiovascular complications in patients with type 2 diabetes mellitus even in preclinical stages of disease. To the best of our knowledge, there is limited researches in this regard among patients with type 1 diabetes. The aim of this study was to evaluate hematologic indices indicating PLT activity in children with type 1 diabetes. This was a case-control study which was conducted on 166 inpatients in 17 Shahrivar children hospital, Rasht, Iran during April 2016 to April 2017. Cases and controls were 83 children with type 1 diabetes mellitus and 83 childre...
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Original Articles Source Type: research
Publication date: Available online 23 April 2019Source: Journal of Clinical &Translational EndocrinologyAuthor(s): Abdishakur Abdulle, Claire K. Inman, Abdelkarim Saleh, Mohamed Noshi, Divya Galani, Laila Abdelwareth, Habiba Alsafar, Abubaker Elfatih, Hefsa Al Shamsi, Raghib Ali, Huilin Li, Ravichandran Ramasamy, Ann Marie Schmidt, Mahmoud M. Benbarka, Mohamed H. HassanAbstractBackgroundThe United Arab Emirates is experiencing increasing rates of type 2 diabetes (T2D) and its complications. As soluble levels of the receptor for advanced glycation end products, (sRAGE), and endogenous secretory RAGE (esRAGE), the latter...
Source: Journal of Clinical and Translational Endocrinology - Category: Endocrinology Source Type: research
ConclusionVitamin D level appeared to be lower in diabetic patients and is associated with poor glycemic control &microalbuminuria.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionSGLT2 inhibitors have relatively safe profiles and can efficiently decrease HbA1c as well as fasting and postprandial glucose levels. Furthermore, SGLT2 inhibitors administrations are not associated with significant hypoglycemic episodes or weight gain. Thus, combination of SGLT2 inhibitors and other less harmful anti-diabetic medicines could be considered if there is no any contraindication.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
ConclusionImbalance between AngiotensinII – Angiotensin1-7 is associated with increased inflammation and vascular dysfunction in diabetics and can contribute to development of hypertension in these patients.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
Publication date: Available online 23 April 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Azza Khalifa Bin Hussain, Elamin Abdelgadir, Fauzia Rashid, Abeer Al Haj, Puja Thadani, Alaaeldin M.K. BashierAbstractFor more than a century, the high occurrences of coronary and peripheral artery diseases in diabetes mellitus patients has been well recognised; despite that, the ability to improve CV event rates by optimizing glycaemic control has remained elusive. Nevertheless, the last decade has seen several cardiovascular outcome clinical trials (CVOTs) of many antihyperglycemic agents tha...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - Category: Endocrinology Source Type: research
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