Assessment of mGluR5 KO mice under conditions of low stress using a rodent touchscreen apparatus reveals impaired behavioural flexibility driven by perseverative responses

Genetic and pharmacological manipulations targeting metabotropic glutamate receptor 5 (mGluR5) affect performance in behavioural paradigms that depend on cognitive flexibility. Many of these studies involved e...

Source: Molecular Brain - April 11, 2019 Category: Neuroscience Authors: Jisoo Lim, Eosu Kim, Hyun Jong Noh, Shinwon Kang, Benjamin U. Phillips, Dong Goo Kim, Timothy J. Bussey, Lisa Saksida, Christopher J. Heath and Chul Hoon Kim Tags: Research Source Type: research