Cellulitis and erysipelas: antimicrobial prescribing DRAFT guidance consultation

This DRAFT guideline sets out an antimicrobial prescribing strategy for cellulitis and erysipelas. It aims to optimise antibiotic use and reduce antibiotic resistance. It does not cover diagnosis. Registered Stakeholders have until 10 May 2019 to comment.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Acne affects 85% of individuals and is responsible for a greater global burden of disease than psoriasis and cellulitis. However, our understanding of potential racial/ethnic and sex differences in healthcare utilization and treatment is limited. We evaluated factors associated with healthcare utilization and specific treatments for acne with a goal of identifying disparities in acne care. We performed a cohort study using the OptumInsights Electronic Health Record Database between July 1, 2007 and June 30, 2017 among patients with acne.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Epidemiology Source Type: research
In this study, we investigated the antibacterial effect of methanol extracts of the fruit, stem, and leaf of LCE (LCEEs) against S. pyogenes using disk diffusion assay. As LCEE (fruit) had the strongest antibacterial activity among the three LCEEs, we focused on functional analysis of antibacterial effects of LCEE (fruit). LCEE (fruit) suppressed the growth of S. pyogenes in a dose-dependent manner. Morphological analysis by transmission electron microscopy demonstrated that LCEE (fruit) damaged the shape of S. pyogenes. Microplate and confocal laser microscopy analysis showed that biofilm formation was also suppressed by ...
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
AbstractThe fascial system is a continuum of connective tissues present everywhere throughout the body that can be locally involved in a large variety of disorders. These disorders include traumatic disorders (Morel-Lavall ée lesion, myo-aponeurotic injuries, and muscle hernia), septic diseases (necrotizing and non-necrotizing cellulitis and fasciitis), and neoplastic diseases (superficial fibromatosis, desmoid tumors, and sarcomas). The current pictorial review aims to focus on these localized disorders involving th e fasciae of the musculoskeletal system and their appearance at MRI.
Source: Insights into Imaging - Category: Radiology Source Type: research
ConclusionThe possibility that LVA could become an excellent therapy for similar cases is suggested.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We report the case of an 85-year-old patient who developed lower limb cellulitis caused byV. parahaemolyticus, originating from leg ulcers and complicated by septicaemia and septic shock, after a sea beach holiday. We discuss the epidemiology, pathogenesis, clinical manifestations and treatment ofV. parahaemolyticus infections.Case Rep Dermatol 2019;11:94 –100
Source: Case Reports in Dermatology - Category: Dermatology Source Type: research
Conditions:   Hysterectomy;   Cellulitis;   Vaginosis;   Abscess;   Cuff Interventions:   Drug: cephalosporin + Metronidazole Vaginal;   Drug: cephalosporin + Placebos Sponsors:   CES University;   Lafrancol S.A.;   Prolab S.A;   Clínica del prado;   Clínica comfamiliar pereira Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractPurpose of ReviewOver recent years, there has been a marked increase in the number of centres delivering paediatric outpatient parenteral antimicrobial therapy (pOPAT). Various factors have fuelled this drive, including the significant economic pressures faced by high-income countries to contain the cost of healthcare, resulting in a significant reduction of in-patient beds over the past 20  years. It is essential that pOPAT services have formal clinical governance structures in place to ensure the safe and effective management of children being ambulated on intravenous antibiotics. They also require oversight...
Source: Current Infectious Disease Reports - Category: Infectious Diseases Source Type: research
To the Editor:
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
AbstractPurpose of reviewPatients with cirrhosis are at high risk of developing serious infections. Bacterial infections remain the most common cause of morbidity and mortality in these patients. This review is focused on the prevalence of infections in those with cirrhosis, including multidrug-resistant (MDR) pathogens, pathogenesis of infection-related acute-on-chronic liver failure (ACLF), current treatment recommendations, and prophylactic strategies in patients with cirrhosis.Recent findingsRecent epidemiological studies have noted an emerging prevalence of MDR bacterial infections and associated with poor prognosis, ...
Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research
Publication date: Available online 10 April 2019Source: Journal of Microbiology, Immunology and InfectionAuthor(s): Meng-Shiuan Hsu, Chun-Hsing Liao, Chi-Tai FangAbstractIn this prospective study of 89 patients with acute cellulitis, we showed nasal swab culture of methicillin-resistant S. aureus (MRSA), taken at enrollment, has a high specificity of 95% in predicting MRSA cellulitis among the 24 patients whose cellulitis became purulent. However, the sensitivity is only 20%.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
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