Idiopathic ventricular fibrillation with repetitive activity inducible within the distal Purkinje system

Ventricular ectopy mostly originating from the distal Purkinje system, are observed in approximately 30% of idiopathic ventricular fibrillation (VF)1-5. These ectopy have commonly short coupling R-on-T intervals. However the Purkinje triggers are often transient, only present during short arrhythmic periods, thus preventing the recognition of this condition and its treatment. Here, we report two cases of idiopathic VF in which altered electrophysiological properties and inducible repetitive activity were demonstrated in the peripheral Purkinje system in the absence of clinical short-coupled ectopy.

Source: Heart Rhythm - April 9, 2019 Category: Cardiology Authors: Michel Haissaguerre, Ghassen Cheniti, William Escande, Alexandre Zhao, M élèze Hocini, Olivier Bernus Source Type: research