Rubella (German measles) revisited.

Rubella (German measles) revisited. Hong Kong Med J. 2019 Apr 10;: Authors: Leung AKC, Hon KL, Leong KF Abstract Rubella is generally a mild and self-limited disease in children. During pregnancy, rubella can have potentially devastating effects on the developing fetus. Postnatal rubella is transmitted primarily by inhalation of virus-laden airborne droplets or direct contact with infected nasopharyngeal secretions. In susceptible pregnant women, the virus may cross the placenta and spread through the vascular system of the developing fetus. Postnatally acquired rubella typically begins with fever and lymphadenopathy, followed by an erythematous, maculopapular rash. The rash classically begins on the face, spreads cephalocaudally, becomes generalised within 24 hours, and disappears within 3 days. Maternal rubella, especially during early pregnancy, may lead to miscarriage, intrauterine fetal death, premature labour, intrauterine growth retardation, and congenital rubella syndrome. Cataracts, congenital heart defects, and sensorineural deafness are the classic triad of congenital rubella syndrome and they typically occur if the fetal infection occurs in the first 11 weeks of gestation. Laboratory confirmation of rubella virus infection can be based on a positive serological test for rubella-specific immunoglobulin M antibody; a four-fold or greater increase in rubella-specific immunoglobulin G titres between acute and convalescent sera; or detection of ru...
Source: Hong Kong Med J - Category: General Medicine Authors: Tags: Hong Kong Med J Source Type: research

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Authors: Fournier E Abstract Carpal tunnel syndrome (CTS) is too common a condition not to daily interact with the practitioner, if only because of its entanglement to other pathologies, causal or chance association. The typical symptomatology, with hand paresthesia and morning pain upon waking, is related to a median nerve injury in the confined space of the carpal tunnel, more often by local inflammation and tenosynovitis of the finger flexors (repetitive activity of the hands). SCC may be secondary to situations (pregnancy) or conditions (edema, hypothyroidism…), which exaggerate the ordinary pathophysiol...
Source: Revue de Medecine Interne - Category: Internal Medicine Tags: Rev Med Interne Source Type: research
Publication date: Available online 26 January 2020Source: Regional Science and Urban EconomicsAuthor(s): Fédéric Holm-HadullaAbstractThis paper studies the impact of redistributive fiscal equalization transfers on the choice between a distortionary capital tax and a non-distortionary land tax at the local layer of government. In a standard tax competition model, the paper shows that this impact is ambiguous in that: depending on the motives driving local policy choices, fiscal equalization may either induce a more or a less distortionary tax structure. Using a natural experiment from German municipal finance,...
Source: Regional Science and Urban Economics - Category: Science Source Type: research
Residents of China's Hubei province, where the new coronavirus outbreak was first reported, will be banned from entering Hong Kong from Monday as China tries to halt the rapid spread of the outbreak.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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Source: Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
Publication date: Available online 25 January 2020Source: Biocybernetics and Biomedical EngineeringAuthor(s): Saqib Saleem, Ahmed Saeed, Shabnam Usman, Javed Ferzund, Jahangir Arshad, Jawad Mirza, Tareq ManzoorAbstractAccording to World Health Organization, 5—18% births around the world are premature, and this rate is on its rise. Recent trend has been to develop computational tools which could support obstetricians in their daily practice. This work is aimed at extracting novel diagnostic features for term vs. preterm births classification based on the dynamics of contraction and non-contractions (dummy) intervals. ...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
In this study, the aim was to characterize the intracellular and extracellular metabolite profiles of different oxidative stress cell models commonly used in the research of pregnancy complications. HTR8/SVneo human trophoblast cell lines were treated with five different oxidative stress‑inducing conditions: Hypoxia (1% oxygen); hypoxia and reoxygenation; cobalt chloride (CoCl2; 300 µmol/l); sodium nitroprusside (SNP; 2.5 mmol/l); and the serum of women with preeclampsia (10% v/v). Intracellular metabolites were extracted from cells and extracellular metabolites were collected from spent media for me...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
In conclusion, GDM was associated with increased placental permeability and this may be linked with changes in TJs. LMWH intervention mediated protection against this GDM‑associated shift in placental permeability via the RAGE/NF‑κB pathway. PMID: 31974593 [PubMed - in process]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Tagliaferri S, Esposito FG, Esposito G, Saccone G, Signorini MG, Magenes G, Campanile M, Guida M, Zullo F Abstract Analysing antepartum and intrapartum computerised cardiotocographic (cCTG) parameters in physiological term pregnancies with nuchal (NC) or body cord (BC), in order to correlate them with labour events and neonatal outcome. We enrolled 808 pregnant women, composed of 264 with 'one NC', 121 with 'multiple NCs', 39 with BC and 384 with 'no NC', were monitored from the 37th week of gestation before labour, while 49 pregnant women with 'one or more NCs' and 47 with 'no NCs' were analysed during la...
Source: Journal of Obstetrics and Gynaecology - Category: OBGYN Tags: J Obstet Gynaecol Source Type: research
Co-director of the National Child Development Study that gathered data from 15,000 children born in one week in March 1958Ron Davie, who has died aged 90, was the former director of theNational Children ’s Bureau, which carries out research and works collaboratively to influence policy and improve services for children and young people, and co-director of the longitudinal National Child Development Study (NCDS) into the physical, educational and social development of children in Britain.The NCDS started in 1958 as the Perinatal Mortality Study, gathering information on the births of 15,000 children born in the week b...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Children Society Health Disability Parents and parenting Psychology Teaching Source Type: news
Officials announce new measures to contain disease, including wildlife trade ban and bus suspensions, as confirmed death toll reaches 56Coronavirus ’s ability to spread getting stronger, China suggestsScientists race to discover how Wuhan victims were infectedWhere has coronavirus spread?4.41pmGMT3.56pmGMT Jonathan Ashworth, the UK ’s shadow health secretary, urged the government to reassure the public it is sufficiently prepared as the NHS is already struggling in the flu season.He told the Guardian:The NHS is currently under immense strain this winter with staff already working flat out and hospitals overcrow...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak China Health Asia Pacific Society Science World news Americas Europe Australia news France Hong Kong Infectious diseases Source Type: news
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