Modulation of Host-Pathogen Communication by Extracellular Vesicles (EVs) of the Protozoan Parasite Leishmania

In conclusion, we hope that this review brings about a new and more in-depth understanding of the part that Leishmania exosomes and various infectious agents play in the context of host-parasite interactions, with a particular focus on the establishment of infection. Future research in this field of investigations is critical for the development of new vaccine and diagnostic tools. Author Contributions The first draft was done by MO. AF and GD added new information. Funding Research in MO laboratory is supported by the Canadian Institute of Health Research (grant number: PJT-159765) and the Natural Sciences and Engineering Research Council (grant number: RGPIN-2018-03849) of Canada. AF is recipient of a studentship from Science without Border (Brazil). GD is recipient of a studentship from the experimental medicine program of McGill University. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. References Abu-Dayyeh, I., Shio, M. T., Sato, S., Akira, S., Cousineau, B., and Olivier, M. (2008). Leishmania-induced IRAK-1 inactivation is mediated by SHP-1 interacting with an evolutionarily conserved KTIM motif. PLoS Negl. Trop. Dis. 2:e305. doi: 10.1371/journal.pntd.0000305 PubMed Abstract | CrossRef Full Text | Google Scholar Admyre, C., Johansson, S. M., Qazi, K. R., Filen, J. J., Lahesmaa, R., Norman, M., et al...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research