Mystery E. coli outbreak expands. 96 people sickened in 5 states, CDC says

More people are sick from a multistate outbreak of E. coli from an unknown source, the US Centers for Disease Control and Prevention said Tuesday. The total number of people infected is now 96. That's 24 more than the agency initially reported on Friday.
Source: - Health - Category: Consumer Health News Source Type: news

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We describe the unexpected binding of S-layer to cells devoid of DC-SIGN but also confirm that the presence of DC-SIGN was essential for S-layer’s antiviral activity. S-layer protein exerted its antiviral effect with different kinetics than mannan, a known viral inhibitor that also acts on DC-SIGN (Yu et al., 2017). Together our results suggest that inhibition of viral entry by S-layer occurs via a novel S-layer/DC-SIGN interaction. Materials and Methods Isolation of S-Layer Proteins S-layer proteins were extracted from overnight cultures of L. acidophilus ATCC 4356 cells grown in MRS medium at 37°C by using 6...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In this study, the multivariate linear mixed model (LMM) was used to calculate the P-value to determine interesting SNPs at each time point using GEMMA software v0.97 (Zhou and Stephens, 2014). Growth data from both untreated and vancomycin-treated group formed the bivariate phenotype, which differs hugely from the univariate phenotype. Therefore, LMM developed for univariate phenotype cannot be applied to analyze correlated phenotype directly; methods allowing LMM algorithm specific to multivariate and correlated phenotype [multivariate LMMs (mvLMMs)] are in urgent need. GEMMA software could extend a standard LMM to mvLMM...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
This study was supported by the Israel Institute for Biological Research, Ness Ziona, Israel. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments We thank Dr. Vered Caspi (Ben-Gurion University) for assisting with the bioinformatics and statistical analyses of the Agilent DNA microarray results. Supplementary Material The Supplementary Material for this article can be found online at:
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Jennifer M. Rudd1, Sivasami Pulavendran1, Harshini K. Ashar1, Jerry W. Ritchey1, Timothy A. Snider1, Jerry R. Malayer1, Montelongo Marie1, Vincent T. K. Chow2 and Teluguakula Narasaraju1* 1Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, United States2Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore Exaggerated host innate immune responses have been implicated in severe influenza pneumonia. We have previously demonstrated that excessive neutrophils recruited during in...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Vega Masignani1, Mariagrazia Pizza1 and E. Richard Moxon2* 1GSK Vaccines, Siena, Italy 2Department of Pediatrics, Oxford University, Oxford, United Kingdom The discovery of vaccine antigens through whole genome sequencing (WGS) contrasts with the classical hypothesis-driven laboratory-based analysis of microbes to identify components to elicit protective immunity. This radical change in scientific direction and action in vaccine research is captured in the term reverse vaccinology. The complete genome sequence of an isolate of Neisseria meningitidis serogroup B (MenB) was systematically analyzed to identify prot...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Centers for Disease Control and Prevention on Friday said no common supplier, distributor or brand of the meat has been identified
Source: Health News: - Category: Consumer Health News Source Type: news
There have now been 109 reported cases in 6 states with 17 hospitalizations, according to the CDC.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
The CDC was perplexed over the source of a multistate E. coli outbreak.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
AbstractNorovirus (NoV) is the leading cause of acute viral gastroenteritis outbreaks in the world. These outbreaks are frequently associated with bivalve shellfish consumption, particularly because these products are often eaten raw or only slightly cooked. In Morocco, regulations concerning the acceptable levels of enteric bacteria indicator organisms in these products have been put in place. However, these regulations do not take into account the risk of viral contamination, and many gastroenteritis outbreaks have been linked to the ingestion of bivalve shellfish from areas that comply with the current food safety crite...
Source: Food and Environmental Virology - Category: Virology Source Type: research
The U.S. Centers for Disease Control and Prevention said on Friday preliminary information suggested ground beef could be responsible for a recent E.coli outbreak that has spread across six states.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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