Measurement of Forearm Bone Density by Dual Energy X-ray Absorptiometry Increases the Prevalence of Osteoporosis in Men with Celiac Disease

Guidelines advise measurement of bone mineral density (BMD) in patients with a diagnosis of celiac disease. The lumbar spine (LS) and hip sites are usually measured. Although skeletal sites rich in trabecular bone are believed to be vulnerable to osteoporosis in patients with celiac disease, most studies have not measured the cortical distal 1/3-radius.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research

Related Links:

Introduction: Compared to the general population, patients with coeliac disease are at an increased risk of low bone mineral density (osteopenia) and osteoporosis and this is a risk for bone fracture [1,2]. Recently published NICE guidelines on the management of coeliac disease (2015) recommend assessment of bone mineral density (BMD) at annual review using the WHO fracture risk assessment tool before consideration of the need for a dual-energy X-ray absorptiometry (DXA) scan [3,4]. Under these guidelines, it is not routine to extend this assessment to those below the age of 50 years, unless major risk factors additive to ...
Source: Clinical Nutrition ESPEN - Category: Nutrition Authors: Source Type: research
Conclusions: We document low adherence of physicians to recommended guidelines to recommendations to screen for osteopathy in CD. Vitamin D deficiency and low BMD are highly prevalent among Saudi CD patients. This may be a reflection of the low vitamin D stores in the Saudi general population.
Source: The Saudi Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research
This study aimed to evaluate if the FRAX tool can replace or optimize the use of DXA scan in celiac disease (CD). We prospectively enrolled all CD patients aged over 40  yr diagnosed at our third-level unit. At time of CD diagnosis, all patients underwent FRAX score calculation for risk of major osteoporotic and hip fractures and DXA scan (used as gold standard) to assess the accuracy of the FRAX score.
Source: Journal of Clinical Densitometry - Category: Radiology Authors: Tags: Original Article Source Type: research
AbstractObjectivesTo study bone mineral density (BMD) and standard serum biochemical indices among newly diagnosed and already diagnosed cases of Celiac Disease (CD) on gluten free diet for at least one year.MethodsThis hospital based analytic, observational study was done at a tertiary care centre, from April 2013 through June 2014. Thirty six children (20 females) with untreated CD at diagnosis (Group A) and 36 age and sex matched children on gluten-free diet for at least one year (Group B) were studied. Serum measurements of biochemical bone health indices and BMD, assessed by dual X-ray absorptiometry, were obtained.Re...
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Abstract More than 50 % of untreated patients with celiac disease (CD) have bone loss detected by bone densitometry (dual-energy X-ray absorptiometry:DXA). Moreover, patients with CD are more likely to have osteoporosis and fragility fractures, especially of the distal radius. Although still controversial, we recommend DXA screening in all celiac disease patients, particularly in those with symptomatic CD at diagnosis and in those who present risk factors for fracture such as older age, menopausal status, previous fracture history, and familial hip fracture history. Bone microarchitecture, especially the trab...
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research
Conclusions: Within our cohort of patients with coeliac disease, inflammatory bowel disease was significantly more common (3,2 %) than in the general population.
Source: BMC Gastroenterology - Category: Gastroenterology Authors: Source Type: research
ConclusionThis study demonstrated that 69% of Brazilian patients with celiac disease at diagnosis had low bone mineral density, being more frequent in women older than 50 years.ContextoBaixa densidade mineral óssea é considerada uma manifestação extra-intestinal da doença celíaca com redução da massa óssea, aumento da fragilidade óssea e risco de fraturas. A doença celíaca é considerada uma condição de alto risco para a osteoporose secundária e a avaliação da densidade óssea é muito im...
Source: Arquivos de Gastroenterologia - Category: Gastroenterology Source Type: research
ConclusionDietary compliance is associated with a high chance of healing the intestinal lesion and correction of specific body compositional abnormalities. The time‐course differed with body fat improving within one year, and correction of the mucosal lesion and improvement in lean mass and bone mass taking longer. This article is protected by copyright. All rights reserved.
Source: Journal of Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Original Article ‐ Gastroenterology (Clinical) Source Type: research
AbstractClinical and research applications of dual-energy X-ray absorptiometry in childhood are reviewed. Originally used for bone mineralization assessment in adults with osteoporosis, total body dual-energy X-ray absorptiometry is now also used currently alone or combined with other techniques for assessment of fat mass and fat-free mass. Low invasiveness, accuracy, swiftness and availability of pediatric software make total-body dual-energy X-ray absorptiometry suitable for studying body composition in a wide variety of metabolic and nutritional disorders in childhood such as simple or genetic obesity, insulin-dependent...
Source: Annals of Diagnostic Paediatric Pathology - Category: Pathology Source Type: research
More News: Celiac Disease | Coeliac Disease | DEXA Scan | Gastroenterology | Orthopaedics | Osteoporosis | Study