Adenosine kinase deficiency makes liver more susceptible to carcinogen

(Mary Ann Liebert, Inc./Genetic Engineering News) A new study has shown that reduced adenosine kinase expression in the liver can make it more susceptible to carcinogenic damage and the development of liver cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news

Related Links:

Authors: Bozkurt S, Park JI, Kan KM, Ferrari M, Rubin DL, Brooks JD, Hernandez-Boussard T Abstract Digital rectal examination (DRE) is considered a quality metric for prostate cancer care. However, much of the DRE related rich information is documented as free-text in clinical narratives. Therefore, we aimed to develop a natural language processing (NLP) pipeline for automatic documentation of DRE in clinical notes using a domain-specific dictionary created by clinical experts and an extended version of the same dictionary learned by clinical notes using distributional semantics algorithms. The proposed pipeline wa...
Source: AMIA Annual Symposium Proceedings - Category: Bioinformatics Tags: AMIA Annu Symp Proc Source Type: research
Beyond Meat has dropped from its website statistics about the health risks of eating meat. The move follows criticism from experts about the company's health claims, but Beyond Meat said it's simply updating its site.
Source: CBC | Health - Category: Consumer Health News Tags: News/Business Source Type: news
CONCLUSION: Audio-visual navigation enables to significantly reduce the treatment time in comparison with DIBH without A-V feedback. PMID: 31602046 [PubMed - as supplied by publisher]
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
CONCLUSION: MRI/TRUS TG in combination with SB had significantly higher detection rates than SB in the RB group only. Differences in detection rates between examiners were dependent on the level of previous experience with TRUS guided biopsy. PMID: 31602045 [PubMed - as supplied by publisher]
Source: Biomedical Papers of the Medical Faculty of the Univ Palacky Olomouc Czech Repub - Category: Biomedical Science Tags: Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub Source Type: research
Men who conceive children using assisted reproduction techniques (ART) like in vitro fertilization (IVF) are more likely to develop prostate cancer and may benefit from screening, a study suggests.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
This study aims to analyze the prognostic importance of serum PSA response in patients who received radioligand therapy (RLT) with Lu-177 Prostate-specific membrane antigen (PSMA) for their castration-resistant prostate cancer. METHODS: Thirty consecutive patients who received Lu-177 PSMA treatment for their castration-resistant prostate carcinoma were included. All the patients had undergone Ga-68 PSMA PET/CT scanning before Lu-177 PSMA therapy, which revealed multiple metastases. Patients were treated with a fixed dose (180 mCi) of Lu-177 PSMA at six to eight weeks intervals. Prostate specific antigen (PSA) response ...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Publication date: Available online 11 October 2019Source: Biosensors and BioelectronicsAuthor(s): Weiqing Xu, Lei Jiao, Huarong Ye, Zhenzhong Guo, Yu Wu, Hongye Yan, Wenling Gu, Dan Du, Yuehe Lin, Chengzhou ZhuAbstractEstrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor-2 (HER2) are the three crucial biomarkers for the clinical diagnosis of breast cancer. Sensitive and precise detection of ER, PR, and HER2 is of great significance for the diagnosis of breast cancer. Herein, through a simple solvent-induced self-assembly process, the self-carried allochroic nanoparticles were prepar...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Publication date: Available online 11 October 2019Source: Life SciencesAuthor(s): Mohammad Amin Javidi, Ayat Kaeidi, Seyedeh Sahar Mortazavi Farsani, Sadegh Babashah, Majid SadeghizadehAbstractAimsAn important obstacle on the way of cell-based therapy is the risk of tumorigenicity in the patients benefit from these transplanted cells due to undifferentiated cells which participate in transplantation. Curcumin, the main compound of spice turmeric -as one of the natural products-was demonstrated to possess effective anti-cancer properties, with no significant effect on normal cells in dose and/or time-dependent manner. Furth...
Source: Life Sciences - Category: Biology Source Type: research
In conclusions, TTN-AS1 promoted CRC proliferation and invasion through miR-376a-3p/KLF15 axis. Our findings suggested that TTN-AS1 might be a potential therapeutic target in CRC treatment.
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 11 October 2019Source: Life SciencesAuthor(s): Xiurui Lv, Yang Li, Yuhan Li, Hongxing Li, Lingling Zhou, Binyu Wang, Zhengke Zhi, Weibing TangAbstractLong noncoding RNAs (lncRNAs) are characterized as a group of endogenous RNAs that are more than 200 nucleotides in length and have no protein-encoding function. More and more evidence indicates that lncRNAs play vital roles in various human diseases, especially in tumorigenesis. Focally amplified lncRNA on chromosome 1 (FAL1), a novel lncRNA with enhancer-like activity, has been identified as an oncogene in multiple cancers and high express...
Source: Life Sciences - Category: Biology Source Type: research
More News: Cancer | Cancer & Oncology | Genetics | Liver | Study | Urology & Nephrology