Functional Gastrointestinal Disease in Autism Spectrum Disorder: A Retrospective Descriptive Study in a Clinical Sample

Conclusions: Almost one-third of ASD patients in our sample had at least one fGID. The presence of fGID was associated with ID, sleep problems and with behavioral problems (as measured by the prescription of psychotropic drugs). This subsample of ASD patients with fGID deserves particular attention in future research projects, focusing on specific phenotypic characteristics and overlapping biological markers that may underlie both pathologies. Introduction Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized by impairments in social communication and restricted, repetitive patterns of behavior, interests, or activities (1). The neurobiological basis of ASD seems incontrovertible (2) even though the neurobiological mechanisms that result in the clinical phenotype remain to be fully elucidated. These include genetic factors, neuropathology, neurostructure, and brain networks (2). According to previous studies, more than 70% of individuals with ASD have other concurrent medical, developmental, or psychiatric conditions, which are frequently multiple (3–6). It is widely reported that children with ASD are more likely to experience unmet medical needs compared with typically developing children (7). According to data from a US national survey, among children and adolescents with special health care needs, those with ASD are more likely to require specific health care services. This also holds true when compared with children who have...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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This study investigated the association of the five-factor model and trait emotional intelligence (trait EI) with camouflaging behaviours (masking and compensating for autistic characteristics) in a large sample of 278 autistic and 230 typically developing (TD) participants. Participants completed questionnaires assessing autistic traits, big five personality, trait EI, and social camouflaging of autistic traits. Camouflaging was negatively related to extraversion, agreeableness, and conscientiousness, while it was positively related to neuroticism. Trait EI was also negatively linked to camouflaging. The differences betwe...
Source: Personality and Individual Differences - Category: Psychiatry & Psychology Source Type: research
Conclusions: The new instrument allows healthcare professionals to assess the level of person-centered care provided by gerontology centers with excellent reliability and validity.ResumenAntecedentes/Objetivo: Las residencias y otros servicios gerontológicos son frecuentemente criticados por su falta de flexibilización y personalización en la atención, conduciendo a un trato uniforme que dificulta el control sobre sus vidas. El objetivo del trabajo es desarrollar y validar el primer instrumento de medida español que permite a los profesionales de la salud evaluar en qué medida se l...
Source: International Journal of Clinical and Health Psychology - Category: Psychiatry & Psychology Source Type: research
In this report, Nancy R. Reynolds describes the resolutions adopted at this year's World Health Assembly, which she attended, and their importance to nurses in the United States and globally. Reynolds is a professor and associate dean of global affairs at the Johns Hopkins University School of Nursing in Baltimore, Maryland. She is also the co–secretary general of the Global Network of WHO Collaborating Centers for Nursing and Midwifery, the Secretariat of which is currently based at Johns Hopkins University.
Source: AJN - Category: Nursing Tags: AJN Reports Source Type: research
Conclusions: No safety concerns were identified from this retrospective EHR review of hospitalized adults who received a milk and molasses enema for constipation relief. The findings indicate that this treatment is safe, although further study examining its efficacy in this population is needed.
Source: AJN - Category: Nursing Tags: Feature Articles Source Type: research
Abstract Ischemic colitis primarily affects the elderly with underlying disease, but it rarely occurs in young adults with risk factors, such as coagulopathy or vascular disorder. Moreover, it is extremely rare in the very young without risk factors. This paper presents a patient with ischemic colitis associated with heat stroke and rhabdomyolysis after intense exercise under high-temperature conditions. A 20-year-old man presented with mental deterioration after a vigorous soccer game for more than 30 minutes in sweltering weather. He also presented with hematochezia with abdominal pain. The laboratory tests reve...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Pancreatic cancer is associated with a poor prognosis and high mortality. Thus, distress that includes depression and anxiety is a relatively common comorbidity for patients suffering from pancreatic cancer. However, these psychological symptoms are likely to be under-detected and undertreated. Regarding high levels of unmet needs of psychological support for patients with pancreatic cancer, early screening for distress and adequate interventions should be considered in palliative care settings. Suicide, a common but preventable cause of mortality for patients with pancreatic cancer, also deserves the fur...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
Abstract Pancreatic cancer is a dismal disease with a poor prognosis and is one of the most painful malignancies. Therefore, adequate pain control is essential to improving the patient's quality of life. Pain in pancreatic cancer has complex pathophysiologic mechanisms and different characteristics. The choice of pain management modalities should be individualized depending on the pain characteristics using a multidisciplinary approach. The treatment options available include medical treatment, chemotherapy, celiac plexus/ganglion neurolysis, radiotherapy, and endoscopic technique. This review discusses the medica...
Source: Korean J Gastroenter... - Category: Gastroenterology Authors: Tags: Korean J Gastroenterol Source Type: research
ConclusionsEpilepsy occurs in approximately 75.3% (58/77) of patients. Hypomelanotic macules occurred significantly more often in patients with TSC2 mutations and cases with TSC1/TSC2 mutations had a significantly higher frequency of cortical nodule than patients with no mutations identified. Overall, our data expands the spectrum of mutations associated with the TSC loci and will be of value to the genetic counseling in patients with the disease.
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 23 August 2019Source: SeizureAuthor(s): Alessandro Orsini, Angelo Valetto, Veronica Bertini, Mariagrazia Esposito, Niccolò Carli, Berge A. Minassian, Alice Bonuccelli, Diego Peroni, Roberto Michelucci, Pasquale StrianoAbstractProgressive Myoclonus Epilepsies (PMEs) are a group of uncommon clinically and genetically heterogeneous disorders characterised by myoclonus, generalized epilepsy, and neurological deterioration, including dementia and ataxia. PMEs may have infancy, childhood, juvenile or adult onset, but usually present in late childhood or adolescence, at variance from epil...
Source: Seizure - Category: Neurology Source Type: research
ConclusionThis study showed that the number of male patients with epilepsy driving cars was extremely high, accounting for almost all the patients in this study, with most of them doing several wrong practices during driving. Other major issues include the lack of specific laws regulating driving for patients with epilepsy and no counseling from physicians about driving after the diagnosis of epilepsy. We recommend developing the Saudi driving regulations for patients with epilepsy, and this study is considered an urgent call for action for the formation of a local driving regulations taskforce. Health education about the ...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
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