Molecular Characterization and Antifungal Susceptibility of Clinical Fusarium Species From Brazil

Conclusion In conclusion, F. keratoplasticum and F. petroliphilum were the most frequent species in this study. Amphotericin B showed lower MICs against Fusarium species whereas the antifungal azoles and the fungicide difenoconazole exhibited higher MICs against FSSC. Ethics Statement Samples were collected during routine patient care and the study was retrospective, therefore it was determined by the local Institutional Review Board of the Hospital de Clínicas, Federal University of Paraná and CAPES that ethical clearance was not indicated. Author Contributions PH, AA-H, FQ-T, and JM designed the study. PH and AA-H performed the experiments and wrote the first draft. RP, MM, MN, FQ-T, GH, and JM analyzed the data and revised the manuscript. All authors contributed to the writing and approved the final manuscript. Funding The work of PH was supported by Coordination for the Improvement of Higher Education Personnel, but is currently supported by “Instituto Nacional de Ciência e Tecnologia de Inovação em Doenças de Populações Negligenciadas.” Conflict of Interest Statement JM received grants from F2G and Merck. He has been a consultant to Scynexis and Merck and received speaker’s fees from Merck, United Medical, TEVA and Gilead Sciences. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a poten...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research