Phytochemical Analysis and Evaluation of Antimicrobial Activity of Peumus boldus, Psidium guajava, Vernonia polysphaera, Persea Americana, Eucalyptus citriodora leaf extracts and Jatropha multifida raw sap.

CONCLUSION: All extracts, except from Assa-Peixe, showed promising values against Staphylococcus aureus, with halos varying from 13-20 mm. Analysis of the minimum inhibitory concentration (MIC) values of the six medicinal plants revealed inhibitory activity of S. aureus, with concentrations varying from 3.12-12.5 mg/mL, which is a significant result considering that S. aureus is one of the main causes of hospital infections. In the analysis of the phytochemical profile, Goiaba contained the best yield of phenolic compounds and total flavonoids, as well as higher antioxidant activity by DPPH and phosphomolybdenum, demonstrating that this species contains antioxidant components that can sequester free radicals under in vitro conditions. Therefore, the crude extracts investigated are promising and their antibacterial and antioxidant actions should be thoroughly studied. PMID: 30963968 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Biotechnology - Category: Biotechnology Authors: Tags: Curr Pharm Biotechnol Source Type: research

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Polymicrobial intra-abdominal infections (IAI) are clinically prevalent and cause significant morbidity and mortality, especially those involving fungi. Our laboratory developed a mouse model of polymicrobial IAI and demonstrated that coinfection with Candida albicans and Staphylococcus aureus (C. albicans/S. aureus) results in 80 to 90% mortality in 48 to 72 h due to robust local and systemic inflammation. Surprisingly, inoculation with Candida dubliniensis and S. aureus resulted in minimal mortality, and rechallenge of mice with lethal C. albicans/S. aureus conferred>90% protection up to 60 days postinoculation. Prote...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Host Response and Inflammation Source Type: research
In this study, the effects of dietary administration of lactic acid bacteria (LAB) (Enterococcus faecalis Y17 and Pediococcus pentosaceus G11) on growth performance and immune responses of mud crab were assessed. Both strains (Y17 and G11) showed an inhibitory activity against bacterial pathogens (Aeromonas hydrophila, Vibrio parahaemolyticus, Vibrio alginolyticus, Staphylococcus aureus, and β Streptococcus), and a wide pH tolerance range of 2–10. In vivo, mud crabs were fed a control diet and experimental diets supplemented with 109 cfu g−1 diet either Y17 or G11 for 6 weeks before subjecting to a cha...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
r Mine Kurkcuoglu The essential oil of Meriandra dianthera (Konig ex Roxb.) Benth. (Synonym: Meriandra bengalensis, Lamiaceae) collected from Saudi Arabia was studied utilizing GC and GC/MS. Forty four constituents were identified, representing 96.8% of the total oil. The M. dianthera essential oil (MDEO) was characterized by a high content of oxygenated monoterpenes (76.2%). Camphor (54.3%) was the major compound in MDEO followed by 1,8-cineole (12.2%) and camphene (10.4%). Moreover, MDEO was assessed for its cytotoxic, antimicrobial, and antioxidant activities. MDEO demonstrated an interesting cytotoxic activity ag...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
In conclusion, these data provide meaningful guidance for optimizing amoxicillin regimens to treat infections caused by S. aureus.
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Methicillin-resistant Staphylococcus lugdunensis (MRSL) is increasingly recognized in healthcare and community settings. To obtain a better understanding of the emergence of MRSL, this study characterized the structure and content of the SCCmec elements harboured by 36 MRSL isolates obtained from diverse sources in Hong Kong from 2008 to 2017. The isolates were investigated by whole-genome sequencing. SCCmec types and subtypes were assigned according to the guidelines from the International Working Group on the Classification of Staphylococcal Cassette Chromosome Elements. The sequence type (ST)-SCCmec co...
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
ConclusionsThis investigation of the susceptibility of a range of LA-, HA- and CA-MRSA strains using standardized conditions gave no indication that LA-MRSA strains are less susceptible to commonly used antiseptics compared to HA- and CA-MRSA strains.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
In this study, we analyzed the cutaneous microbiome composition in 7 AD patients and 10 healthy volunteers upon topical coal tar (CT) or vehicle treatment.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
This study aimed to develop novel multifunctional soy protein-based packaging materials with the incorporation of cellulose nanofibril (CNF), Cedrus deodara pine needle extract (PNE), and lactic acid. The effects of the loaded components on the physical and functional properties of nanocomposites were evaluated. Results indicate that the incorporation of CNF into the composite enhanced its tensile strength due to the filling effects of CNF. The addition of CNF and PNE greatly enhanced the light barrier property of films. Moreover, the films containing PNE displayed strong antioxidant activity and significantly improved ant...
Source: Food Packaging and Shelf Life - Category: Food Science Source Type: research
Publication date: Available online 20 July 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Ashwini Lydia Manoharan, Suman Thamburaj, Kasipandi Muniyandi, Gayathri Jagadeesan, Saikumar Sathyanarayanan, Gayathri Nataraj, Parimelazhagan ThangarajAbstractPlants are the natural honorarium used for primary health care and people rely upon herbal medications for the prevention and cure of numerous diseases that are caused by infectious pathogens. The extracts of Elaeocarpus tectorius fruits were successively prepared using five solvents (Petroleum ether, Dichloromethane, Ethyl acetate, Methanol and water) varyin...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Wei-Zhong Liu Three new γ-hydroxyl butenolides (1–3), a pair of new enantiomeric spiro-butenolides (4a and 4b), a pair of enantiomeric cyclopentenones (5a new and 5b new natural), and six known compounds (6–11), were isolated from Aspergillus sclerotiorum. Their structures were established by spectroscopic data and electronic circular dichroism (ECD) spectra. Two pairs of enantiomers [(+)/(–)-6c and (+)/(–)-6d] obtained from the reaction of 6 with acetyl chloride (AcCl) confirmed that 6 was a mixture of two pairs of enantiomers. In addition, the X-ray data confirmed tha...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
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