Heart transplantation in Danon disease: Long term single centre experience and review of the literature.
We report on long term follow up (14.7 years, IQ range 9-21 years) of 4 patients, transplanted for Danon disease cardiomyopathy, showing two LAMP-2 gene variants, the novel c.815T > C and the previously reported c.294G > A. We have also analysed previous published paper on this topic comparing available data from different follow up. Being a skeletal and cardiac muscle disease, with systemic effects, long term results about HTx are indispensable to justify any treatments in this subset of patients.
PMID: 30959184 [PubMed - as supplied by publisher]
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Di Nora C, Miani D, D'Elia AV, Poli S, Maria I, Nucifora G, Finato N, Sponga S, Proclemer A, Livi U Tags: Eur J Med Genet Source Type: research
More News: Cardiology | Cardiomyopathy | Disability | Genetics | Heart | Heart Transplant | Hypertrophic Cardiomyopathy | Science | Transplants