Antibiotic selection and isolate susceptibility profile in patients who failed ciprofloxacin or TMP-SMX for pyelonephritis

We read with interest the retrospective study by Vogler and Pavich assessing treatment failure in women diagnosed with uncomplicated pyelonephritis who were discharged from the emergency department (ED) on an oral fluoroquinolone (FQ) or trimethoprim-sulfamethoxazole (TMP-SMX) versus an oral cephalosporin. The primary endpoint of treatment failure occurred in 0% of patients receiving an oral cephalosporin and 23% of patients receiving FQ or TMP-SMX [1].
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Correspondence Source Type: research