Cystic Fibrosis Transmembrane Conductance Regulator Genotype, Not Circulating Catecholamines, Influences Cardiovascular Function in Patients with Cystic Fibrosis.

Conclusions: Individuals with CF have lower cardiac and peripheral hemodynamic function parameters at rest. Furthermore, these results suggest that impairment in cardiovascular function is likely the result of F508del CFTR genotype, rather than receptor desensitization or inhibited drug delivery. PMID: 30956528 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/30956528?dopt=Abstract

Source: Respiratory Care - April 10, 2019 Category: Respiratory Medicine Authors: Bisch AL, Wheatley CM, Baker SE, Peitzman ER, Van Iterson EH, Laguna TA, Morgan WJ, Snyder EM Tags: Clin Med Insights Circ Respir Pulm Med Source Type: research