Effect of a High-Fat Diet and Metformin on Placental mTOR Signaling in Mice
Conclusion Increased placental mTOR signaling and metformin inhibition of placental mTOR signaling only occurred in the presence of an HFD exposure. These findings suggest that metformin may modulate placental mTOR signaling in the presence of metabolic exposures during pregnancy. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | open access Full text
Source: American Journal of Perinatology Reports - Category: Perinatology & Neonatology Authors: Grace, Matthew R. Dotters-Katz, Sarah K. Zhou, Chunxiao Manuck, Tracy Boggess, Kim Bae-Jump, Victoria Tags: Original Article Source Type: research