Surveillance Report: Chikungunya Virus Disease; Annual Epidemiological Report for 2017

Source: European Union, European Centre for Disease Prevention and Control (ECDC). Published: 4/2019. This six-page report, based on data for 2017 retrieved from The European Surveillance System (TESSy) on December 10, 2018, details how in 2017, 10 countries reported 548 cases of chikungunya virus disease, of which 461 (84.1 percent) were confirmed. For the first time since 2014, autochthonous chikungunya cases were reported from continental Europe by France (n=17) and Italy (n=277). (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news

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don Macrocyclic diterpenoids produced by plants of the Euphorbiaceae family are of considerable interest due to their high structural diversity; and their therapeutically relevant biological properties. Over the last decade many studies have reported the ability of macrocyclic diterpenoids to inhibit in cellulo the cytopathic effect induced by the chikungunya virus. This review; which covers the years 2011 to 2019; lists all macrocyclic diterpenoids that have been evaluated for their ability to inhibit viral replication. The structure–activity relationships and the probable involvement of protein kinase C in ...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
To evaluate the performance of an instrument for predicting chronic Chikungunya arthritis (CCA) in adult patients.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Short communication Source Type: research
CONCLUSION: The extent of the expected risks and attack rates of CHIKV infection might reflect the travel preferences for popular destinations rather than the true risks of CHIKV transmission in travelers' home nonendemic countries. Nevertheless, preventive and blood-safety intervention measures may be applied to returning travelers at risk for infection to reduce CHIKV transfusion threats in their home countries. PMID: 31228360 [PubMed - as supplied by publisher]
Source: Transfusion - Category: Hematology Authors: Tags: Transfusion Source Type: research
de;o Maria de Fátima Vanderlei de Souza Helicteres velutina K. Schum (Sterculiaceae), a member of Malvaceae sensu lato, is a Brazilian endemic plant that has been used by the indigenous tribe Pankarare as an insect repellent. A previous study has reported the isolation of terpenoids, flavonoids and pheophytins, in addition to the larvicidal activity of crude H. velutina extracts derived from the aerial components (leaves, branches/twigs, and flowers). The present study reports the biomonitoring of the effects of fractions and isolated compounds derived from H. velutina against A. aegypti fourth instar larvae. ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
Condition:   Chikungunya Intervention:   Biological: Chikungunya Sponsors:   PaxVax, Inc.;   Walter Reed Army Institute of Research (WRAIR) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Chikungunya Intervention:   Biological: Chikungunya Sponsors:   PaxVax, Inc.;   Walter Reed Army Institute of Research (WRAIR) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
e;o G Abstract Guillain-Barre syndrome (GBS) is one of the main neurologic manifestations of arboviruses, especially Zika virus infection. As known, the prevalence of these diseases is high, so the risk of having an increase on GBS is relevant. The study purposes making a comparative survey between the involvement of dengue, Zika and chikungunya infections in the development of the GBS in Brazil, as well as search in literature resemblances and distinctions between beforehand reported cases. It was performed an electronic search in online databases, with articles published between the years of 2004 to 2018. A tota...
Source: Acta Tropica - Category: Infectious Diseases Authors: Tags: Acta Trop Source Type: research
Abstract Structures of the multiple arthritogenic alphavirus receptor MXRA8 as well as MXRA8 in complex with chikungunya virus (Song et al., Cell, 2019; Basore et al., Cell, 2019) have revealed the mechanism underlying viral invasion and could facilitate the development of novel vaccines and entry inhibitors. PMID: 31221449 [PubMed - as supplied by publisher]
Source: Trends in Microbiology - Category: Microbiology Authors: Tags: Trends Microbiol Source Type: research
Viruses, Vol. 11, Pages 550: Chikungunya Virus Infections in Military Deployments in Tropical Settings—A Narrative Minireview Viruses doi: 10.3390/v11060550 Authors: Hagen Frickmann Ottmar Herchenröder Chikungunya fever is a vector-borne viral disease in subtropical and tropical areas of endemicity. Apart from the burden on local populations, chikungunya virus infection also poses a risk for travelers and, in particular, soldiers during prolonged deployment-associated outdoor activities. The absence of rapid diagnostic tests makes surveillance challenging during military deployments in war and crisis z...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
by Spencer J. Fox, Steven E. Bellan, T. Alex Perkins, Michael A. Johansson, Lauren Ancel Meyers As emerging and re-emerging infectious arboviruses like dengue, chikungunya, and Zika threaten new populations worldwide, officials scramble to assess local severity and transmissibility, with little to no epidemiological history to draw upon. Indirect estimates of risk from vector habitat suitabi lity maps are prone to great uncertainty, while direct estimates from epidemiological data are only possible after cases accumulate and, given environmental constraints on arbovirus transmission, cannot be widely generalized beyond th...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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