Inter-laboratory comparison of Ki-67 proliferating index detected by visual assessment and automated digital image analysis.
CONCLUSION: Proliferation remains one of the most important parameters for tumor characterization helpful in making clinical decisions, but it should be used with great caution. Standardization of the Ki-67 assessment is essential and proliferating index should be expressed as exact numeric value. For patients with proliferative index near the cut-off value, other factors must be considered in making clinical decisions. PMID: 30958325 [PubMed - as supplied by publisher]
Authors: Grandi G, Caroli M, Cortesi L, Toss A, Tazzioli G, Facchinetti F Abstract INTRODUCTION: Risk-reducing-salpingo-oophorectomy (RRSO) inevitably leads BRCA mutation carriers to premature menopause. AREAS COVERED: To evaluate the existing evidence for use of postmenopausal hormone therapy (HT) in BRCAmc, after RRSO or menopause occurring naturally, for both breast cancer (BC) survivors and those without BC. EXPERT OPINION: All BC survivors are excluded from any HT treatment: in other BRCAmc, before 51 years of age the benefits of HT overcome the risks after RRSO and/or premature ovarian insufficie...
CONCLUSIONS: Financial and cultural issues were important hindrances to breast cancer screening in African American women. These findings highlight the importance of affordable health care for preventive health services as well as the relevance of culturally embedded issues to health, while the MQS accentuates the need for more rigorous research articles. Breast cancer screening interventions in this population should attend to barriers identified in this review. PMID: 32641257 [PubMed - as supplied by publisher]
Publication date: Available online 9 July 2020Source: Diagnostic and Interventional ImagingAuthor(s): R. Rella, E. Bufi, P. Belli, F. Petta, T. Serra, V. Masiello, A.R. Scrofani, R. Barone, A. Orlandi, V. Valentini, R. Manfredi
Poor survival outcomes occurred among overweight patients treated with docetaxel-based adjuvant chemotherapy compared with peers given a non-taxane-based regimen.Medscape Medical News
The standard treatment of breast cancer includes a combination of treatment modalities, such as surgery, radiotherapy (RT), chemotherapy and endocrine therapy. RT is administered after breast conserving surgery (BCS) to reduce the risk of locoregional recurrences and improve overall survival[1 –3]. However, RT can cause acute and late toxicity, resulting in a negative impact on health-related quality of life (HRQoL)[4–7]. Breast pain after RT has an important impact on different items of HRQoL.
ConclusionPatients with cancer who need treatment can be treated by taking some measures. These measures include observing individual and collective protection principles in patients and health-care personnel, increasing patients ’ awareness particularly about self-care behavior, performing a COVID-19 test, and taking a chest X-ray, before the treatment starts
AbstractThe purpose of this project was to develop and test the feasibility and preliminary efficacy of a video about cancer clinical trials (CCTs) developed for breast cancer patients. We developed 2 brief 7-min videos that focused on breast cancer patients describing their experiences participating in CCTs, supplemented with doctors and research staff explaining key research concepts. One video was culturally tailored to Black patients and the other to White patients. To assess feasibility study, participants and their care providers completed a survey to evaluate their satisfaction with the video. Eligibility criteria f...
A U.S. House of Representatives subcommittee voted on July 7 to continue delaying...Read more on AuntMinnie.comRelated Reading: ACR: New USPSTF lung cancer guidelines will save lives USPSTF calls for more BRCA1/2 genetic screening, testing ACP pushes breast cancer screening start from 40 to 50 ACR, SBI rebuff new breast cancer screening guidelines Fewer high-risk women get mammography after USPSTF change
CONCLUSION: Core needle biopsy and receptor analysis should be considered on the positive axillary nodes in breast cancer patients. Adjuvant treatment should be targeted to the receptor profile of the lymph node metastases. PMID: 32644312 [PubMed - as supplied by publisher]
Posttraumatic stress disorder (PTSD) is known to affect a subset of cancer survivors. Astudy inPsycho-Oncology found that 6.3% of young survivors of non-metastatic breast cancer reported PTSD symptoms related to cancer more than two years after their diagnosis. Women who reported anxiety symptoms six months after being diagnosed with breast cancer were 12 times more likely than others to report PTSD symptoms two years later.“We found similar rates of cancer-related PTSS [posttraumatic stress symptoms] in breast cancer survivors diagnosed at a young age compared with the general breast cancer population despite their ...