Multiple Comparisons of the Efficacy and Safety for Seven Treatments in Tibia Shaft Fracture Patients

Conclusion: Cast might have the highest probability of the most optimal choice for tibia shaft fracture in close cases, while reamed intramedullary nailing ranked second. Introduction The tibia is a large bone in the lower extremity other than the fibula. A tibia shaft fracture is the most common type of long bone fractures. According to vast clinical data, the causation of diaphyseal fractures of the tibia is usually grouped into two types, bending load and torsion (Johner and Wruhs, 1983). Bending load, led by direct impact injuries, generally of high-velocity trauma, like a car accident, is an increasing fracture cause in modern life and most cases include open fractures with broken skin, even exposed bone. While torsion, low-energy injuries, like falls or sports injuries, is a common cause of closed fractures (Grutter et al., 2000). Pain and regional swelling are clear signs and symptoms. Deformity, distortion and angulation can also be observed (Delee and Stiehl, 1981). In light of AT/OTA, a Comprehensive Classification of Fractures of the Long Bones proposed by the American Orthopedic Trauma Association (OTA), there are three classes: A indicates simple cases, including spiral, oblique (≥30°) and transverse (<30°) fractures; B are fractures with a third or more fragments, but still with contact, like intact wedge fracture, fragmentary wedge fracture; C embodies intact and fragmentary segmental fractures, belonging to multifragmentar...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research