The Pivotal Role of Regulatory T Cells in the Regulation of Innate Immune Cells
This study was provided by the Canadian Institutes of Health Research and the Manitoba Health Research Council. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. References 1. Sprent J, Kishimoto H. The thymus and central tolerance. Philos Trans R Soc Lond B Biol Sci. (2001) 356:609–16. doi: 10.1098/rstb.2001.0846 PubMed Abstract | CrossRef Full Text | Google Scholar 2. Sakaguchi S, Wing K, Miyara M. Regulatory T cells - a brief history and perspective. Eur J Immunol. (2007) 37(Suppl. 1):S116–23. doi: 10.1002/eji.200737593 PubMed Abstract | CrossRef Full Text | Google Scholar 3. Sakaguchi S, Miyara M, Costantino CM, Hafler DA. FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol. (2010) 10:490–500. doi: 10.1038/nri2785 PubMed Abstract | CrossRef Full Text | Google Scholar 4. Weber SE, Harbertson J, Godebu E, Mros GA, Padrick RC, Carson BD, et al. Adaptive islet-specific regulatory CD4 T cells control autoimmune diabetes and mediate the disappearance of pathogenic Th1 cells in vivo. J Immunol. (2006) 176:4730–9. doi: 10.4049/jimmunol.176.8.4730 PubMed Abstract | CrossRef Full Text | Google Scholar 5. Strauss L, Bergmann C, Whiteside TL. Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated ap...
ConclusionsThese data challenge the current dogma linking FDG uptake to the glycolytic rate. They instead introduce a new model considering a strict link between the uptake of this glucose analog, H6PD reticular activity and oxidative damage in diabetes, at least under fasting condition.
ConclusionAccording to the results, whey supplementation significantly reduced the SBP, DBP, HDL, waist circumference, TG and FBS in intervention groups in comparing to control groups.
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Mariceli Comellas, Yamile Marrero, Florence George, Lisa MatthewsAbstractAimTo assess the age and its association with glycemic control (GC) among adults with type 2-diabetes in the United States.Materials and MaterialsData were collected from the National Nutrition Examination Survey (NHANES) 2013 -2014 (n=697), cross-sectional national survey adults with Type2 diabetes. Characteristics included retinopathy diagnosis, blood pressure, albumin-creatinine ratio, hemoglobin A1c (HbA1c), BMI, ch...
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): S. Gentile, F. Strollo, E. Satta, T. Della-Corte, C. Romano, G. Guarino, Nefrocenter Research Study Group: Nephrologists, Diabetologists, NursesSummaryDiabetes Mellitus (DM) is the most common cause of renal failure and ESRD all over the world, and often requires an individualized insulin treatment regimen. Malnutrition, depression-related eating behavior changes, high on-off-dialysis day-to-day glycemic variability and frequent hypoglycemic events occurring during or immediately after dialy...
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Seema Gulati, Anoop Misra
Publication date: Available online 14 November 2019Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Mahdieh Sedighi Pashaki, Jamal Asad Mezel, Zahra Mokhtari, Reza Ghanei Gheshlagh, Parisa Shahbazi Hesabi, Taban Nematifard, Soore KhakiAbstractDepression is one of the most common psychiatric disorders in patients with diabetes, which can exacerbate and accelerate adverse diabetes complaints by reducing self-care behaviors and medication adherence. The purpose of this study is to estimate the prevalence of depression in Iranian patients with diabetes. The search was conducted in the database...
ConclusionSerum CysC is shown to be a superior biomarker in the early diagnosis of DN. However, further studies are still needed to verify our claims.
ConclusionHigh prevalences of underweight and overweight/obesity were identified in ASEAN countries and several correlates were identified which can help to tailor interventions.
New studies from Life for a Child and the American Association of Diabetes Educators shed light on medication cost and access barriers.
Women with ESRD on hemodialysis are rarely screened for osteoporosis despite the fact they are at high risk for bone diseases compared with the general population.Medscape Medical News
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