Emotion Processing, Reappraisal, and Craving in Alcohol Dependence: A Functional Magnetic Resonance Imaging Study

This study, therefore, compares reappraisal of negative, positive, neutral, and alcohol-related images at a behavioral and neural level between ADPs and healthy controls (HCs).Thirty-nine ADPs and 39 age-, gender-, and education-matched HCs performed an emotion reappraisal task during functional magnetic resonance imaging (fMRI), and craving was measured before and after the reappraisal task. During the emotion reappraisal task, participants were instructed to either attend or reappraise positive, negative, neutral, or alcohol-related images, and to indicate their experienced emotion on a visual analogue scale (VAS).Both ADPs and HCs completed the emotion reappraisal task successfully, showing significant differences in self-reported experienced emotion after attending versus reappraising visual stimuli and in brain activity in emotion processing/reappraisal relevant areas. ADPs were not impaired in cognitive reappraisal at a behavioral or neural level relative to HCs, nor did ADPs indicate any difference in self-reported emotion while attending emotional images. However, ADPs were different from HC in emotion processing: ADPs revealed a blunted response in the (posterior) insula, precuneus, operculum, and superior temporal gyrus while attending emotional images compared neutral images compared to HCs, and in ADPs, higher baseline craving levels were associated with a less blunted response to alcohol-related images than in HCs. These results reveal that ADPs do not show impai...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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Conclusions: Proper sample preparation allowed the proteomic and de novo identification of different proteins in the D. melanostictus parotoid macrogland secretion. These results may increase the knowledge about the universe of molecules that compose amphibian skin secretion, as well as to understand their biological/physiological role in the granular gland.
Source: Journal of Venomous Animals and Toxins including Tropical Diseases - Category: Tropical Medicine Source Type: research
Publication date: Available online 19 August 2019Source: PolymerAuthor(s): Fengmei Su, Xiaokang Yang, Beibei Dong, Jingyun Zhao, Fei Lv, Youxin Ji, Chuntai Liu, Liangbin LiAbstractSpontaneously phase transition from form II to I in isotactic polybutene-1 (iPB-1) products during storage at room temperature after processing limited their application. Investigations on phase transition in iPB-1 have practical importance, especially on oriented iPB-1 as oriented form II generated during processing where intense flow field is always imposed. The effects of flow on phase transition were studied with synchrotron radiation scannin...
Source: Polymer - Category: Chemistry Source Type: research
Publication date: Available online 19 August 2019Source: PolymerAuthor(s): Longfei Li, Hong Zhai, Tao Wang, Xibo Qiu, Na Qiang, Peng Dong, Ying Bai, Ai-Yun Peng, Daping QuanAbstractThe ring-opening copolymerization of lactide with carbonate is an available strategy to incorporate reactive groups to the pendent sites of copolymer for further functional modification. A series of random and block copolymers were synthesized from l-lactide (L-LA) and 2-bromomethyl-2-methyltrimethylene carbonate (BMTC) using dodecanol as initiator and stannous octoate as catalyst. The structures of the copolymers were characterized by nuclear m...
Source: Polymer - Category: Chemistry Source Type: research
Dalton Trans., 2019, Accepted Manuscript DOI: 10.1039/C9DT02124H, PaperAmira Siai, Alexandru Oprea, Markus Stroebele, Hans-Juergen Meyer Yellow transparent single crystals of the new compound K2Pb(OCN)I3 were synthesized from a mixture of lead iodide and potassium cyanate through solid-state reaction, which was controlled by the differential scanning... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - Category: Chemistry Authors: Source Type: research
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Conclusion: Breast MRI is an useful tool for the locoregional staging of breast cancer, because it provides useful information that can have a positive impact on patient treatment.Resumo Objetivo: Avaliar o impacto do uso da resson ância magnética (RM) no estadiamento pré-operatório do câncer de mama. Materiais e Métodos: Foram avaliadas 61 pacientes com carcinoma mamário submetidas a RM das mamas, no período de agosto de 2015 a abril de 2016. Um mastologista foi questionado sobre a conduta terapêutica indicada diant e dos dados da paciente e dos exames convencion...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Conclusion: The addition of DWI apparently improves the diagnostic accuracy of MRI in the preoperative assessment of the depth of myometrial invasion in endometrial cancer, which may be particularly helpful in patients for whom contrast agents are contraindicated.Resumo Objetivo: Determinar o valor adicional da difus ão (DWI) em ressonância magnética (RM) na avaliação pré-operatória da invasão miometrial do câncer do endométrio, em comparação com sequências T2 e com o estudo dinâmico após contraste paramagnético (dyn...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip...
Source: Radiologia Brasileira - Category: Radiology Source Type: research
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