The lncRNA MALAT1 rs619586 G Variant Confers Decreased Susceptibility to Recurrent Miscarriage

The lncRNA MALAT1 rs619586 G Variant Confers Decreased Susceptibility to Recurrent Miscarriage Di Che1†, Yanfang Yang2†, Yufen Xu1†, Zhenzhen Fang3, Lei Pi1, LanYan Fu1, Huazhong Zhou1, Yaqian Tan1, Zhaoliang Lu1, Li Li4, Qihua Liang5, Qingshan Xuan4* and Xiaoqiong Gu1,5,6* 1Department of Clinical Biological Resource Bank, Guangzhou Institute of Pediatrics, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China 2Department of Prenatal Diagnosis, Maoming People’s Hospital, Maoming, China 3Program of Molecular Medicine, Guangzhou Women and Children’s Hospital, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China 4Department of Gynecology, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China 5Department of Clinical Lab, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China 6Department of Blood Transfusion, Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, China Cardiovascula disease and recurrent miscarriage have shared risk factors, and some cardiovascular disease-related candidate genes have been confirmed to be associated with recurrent miscarriage. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long non-coding RNA (lncRNA) that is considered to be associated with susceptibility to cardiovascular disease. Howeve...
Source: Frontiers in Physiology - Category: Physiology Source Type: research

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Stats: state of residence: CA race: Asian (Chinese) undergrad: HYPSM major: Computer Science year: senior (taking 1 gap year) cGPA: 3.94 sGPA: 3.96 MCAT: 522 (130/131/129/132) ECs: research: my strongest EC, 2000+ hrs, 2pubs (1 first author, 1 fourth author), won some awards, researching full time during my gap year clinical volunteering: ~150hrs at free clinic, ~100hrs hrs at hospital nonclinical volunteering: started a nonprofit last year that I'll be growing in my gap year, ~200hrs... WAMC? + School List, MCAT: 522, GPA: 3.94, considering MD and MD-PhD
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