Childhood trauma has lasting effect on brain connectivity in patients with depression

(University of Pennsylvania School of Medicine) A study lead by Penn Medicine researchers found that childhood trauma is linked to abnormal connectivity in the brain in adults with major depressive disorder (MDD). The paper, published this week in Proceedings of the National Academy of Sciences (PNAS), is the first data-driven study to show symptom-specific, system-level changes in brain network connectivity in MDD.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news

Related Links:

ConclusionsResults indicated that most clients in home visiting programs tolerated an adverse childhood experience questionnaire well. The findings point to clients who may be more likely to report discomfort and highlight an important association between client and provider discomfort.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Authors: Allali R, Reyre A, Baubet T PMID: 31230759 [PubMed - as supplied by publisher]
Source: L Encephale - Category: Psychiatry Tags: Encephale Source Type: research
ConclusionsThe SHAI is an adequate screening instrument to measure health anxiety in Spanish-speaking community adults.ResumenIntroducción/ObjetivoEl Inventario Breve de Ansiedad por la Salud (SHAI, por sus iniciales en inglés) es un autoinforme ampliamente empleado para evaluar ansiedad por la salud. El objetivo es evaluar la estructura factorial del SHAI, sus propiedades psicométricas, y exactitud diferenciando entre población española no clínica y pacientes con hipocondría.MétodoUn total de 342 participantes extraídos de la población general (66% muje...
Source: International Journal of Clinical and Health Psychology - Category: Psychiatry & Psychology Source Type: research
Condition:   Depression Intervention:   Procedure: Chiropractic Applied Clinical Neuroscience Sponsor:   Life University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Experimental Interventions:   Behavioral: Walking in Urban setting;   Behavioral: Walking in nature setting Sponsors:   McGill University;   Social Sciences and Humanities Research Council of Canada Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Samura K, Miyagi Y, Kawaguchi M, Yoshida F, Okamoto T, Kawashima M Abstract Subthalamic nucleus deep brain stimulation (STN-DBS) improves motor symptoms in individuals with advanced Parkinson's disease (PD) and enables physicians to reduce doses of antiparkinsonian drugs. We investigated possible predictive factors for the successful reduction of antiparkinsonian drug dosage after STN-DBS. We evaluated 33 PD patients who underwent bilateral STN-DBS. We assessed rates of reduction of the levodopa-equivalent daily dose (LEDD) and levodopa daily dose (LDD) by comparing drug doses before vs. 6-months post-surg...
Source: Neurologia Medico-Chirurgica - Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research
Could the advancement of machine and deep learning algorithms be harnessed meaningfully in the area of mental health? Could depression, bipolar disorder, schizophrenia, or any other mental disorder be quantified so that technology could somehow add positively to their diagnostics or treatment? We tried to explore the uses of artificial intelligence in mental health care, and stumbled upon smart algorithms that support clinicians with early detection and diagnostics of mental health issues, with the flagging of suicide risks, and other ones that help patients manage their condition through counselling and constantly being t...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine AI artificial intelligence bipolar disorder chatbots future of psychiatry mental disorder mental health mental health disorders mental health issues moodkit pacifica schizophrenia suicide thriveport woebot Source Type: blogs
Authors: Rubin E PMID: 31230586 [PubMed - as supplied by publisher]
Source: Journal of Social Work in End-of-Life and Palliative Care - Category: Palliative Care Tags: J Soc Work End Life Palliat Care Source Type: research
CONCLUSIONS: Our results suggest a causal role of insomnia in autism spectrum disorder and bipolar disorder. Future disease models should include insomnia as a factor for these two disorders to develop effective interventions. More detailed mechanism studies may also be inspired by this causal inference. PMID: 31234011 [PubMed - as supplied by publisher]
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
CONCLUSION: In this exploratory study on a systemic comparison of thirteen ECT electrode placements, the EF magnitude at regions of interest (ROIs) was highly dependent upon the position of both electrodes, especially the ROIs close to the cortical surface. Compared to conventional right-unilateral (RUL) ECT using a temporo-parietal placement, fronto-parietal and supraorbito-parietal RUL also robustly stimulated brain regions considered important for efficacy, while sparing regions related to cognitive functions, and may be a preferrable approach to the currently used placement for RUL ECT. The simulations also found that ...
Source: Journal of the Association of European Psychiatrists - Category: Psychiatry Tags: Eur Psychiatry Source Type: research
More News: Academies | Brain | Depression | International Medicine & Public Health | Neurology | Science | Study | University of Pennsylvania