Comparison of Graft Acquisition and Early Direct Charges of Haploidentical Related Donor Transplantation versus Umbilical Cord Blood Transplantation

Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative treatment option for advanced or high-risk hematologic malignancies [1]. With shrinking family size and a limited donor pool for ethnic minorities, the availability of an HLA-matched sibling or unrelated donors can be a challenge [2]. In addition, because an unrelated donor search can take up to 4months [3], many high-risk patients can relapse or succumb to their disease while awaiting identification of a suitably matched donor [4].

Source: Biology of Blood and Marrow Transplantation - March 12, 2019 Category: Hematology Authors: Abraham S. Kanate, Aniko Szabo, Renju V. Raj, Kathryn Bower, Rachel Grulke, Nilay Shah, Kelly G. Ross, Aaron Cumpston, Michael Craig, Marcelo C. Pasquini, Nirav Shah, Parameswaran Hari, Mehdi Hamadani, Saurabh Chhabra Source Type: research