Sleep in Offspring of Parents With Mood Disorders

Conclusions: Sleep patterns in children and adolescents were related to the psychiatric diagnosis of their parent(s). Future follow-up of these results may clarify the relations between early sleep differences and the risk of developing mood disorders in individuals at high familial risk.IntroductionSleep disturbances are core symptoms of mood disorders including major depressive disorder and bipolar disorder (1). Additionally, sleep problems have been associated with more severe symptoms, greater functional impairment, and increased risk for relapse among individuals with mood disorders (2). Over 40% of children and youth experience sleep disturbances during development (3). Early sleep disturbances have been shown to predict depressive symptoms (4, 5), manic episodes (6, 7), and psychotic-like experiences (8). However, there have been some inconsistencies in the reported relationship between sleep and psychopathology (9). The persistence of sleep problems may represent a key factor in the true relationship between sleep disturbance in childhood and later mental illness. Many sleep problems resolve during development, but those that persist predict symptoms of depression, anxiety, and externalizing behaviors into adulthood (10). These findings highlight the importance of treating sleep disturbances as a contributing factor to, and not just a symptom of, mood disorders, and emphasize the need for longitudinal investigations of these relationships.Many previous studies examini...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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Authors: Achmat G, Leach L, Onagbiye SO Abstract BACKGROUND: Cardiometabolic disease (CMD) risk factors have reached epidemic proportions, with many people at risk of premature disability and death. There is insufficient data regarding the prevalence of CMD risk factors among firefighters in the Western Cape Province of South Africa. The purpose of this study was to examine the prevalence of CMD risk factors among South African firefighters in the Western Cape Province. Additional outcomes were to determine the relationship between BMI and CMD risk factors among firefighters. METHODS: A total of 219 healthy mal...
Source: Journal of Sports Medicine and Physical Fitness - Category: Sports Medicine Tags: J Sports Med Phys Fitness Source Type: research
Authors: Lapointe-Shaw L, Bell CM PMID: 31613792 [PubMed - in process]
Source: Canadian Medical Association Journal - Category: General Medicine Tags: CMAJ Source Type: research
ConclusionsIn conclusion, PLDRH is a feasible and safe procedure with a learning curve of 65 –70 cases.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
AbstractBackgroundBariatric surgery on patients with body mass index (BMI)  ≥ 50 kg/m2, historically known as superobesity, is technically challenging and carries a higher risk of complications. Bridging interventions have been introduced for weight loss before bariatric surgery in this population. This systematic review and meta-analysis aims to assess the efficacy and safety of bridging interventions before bariatric surgery in patients with BMI  ≥ 50 kg/m2.MethodsMEDLINE, EMBASE, Web of Science, and Scopus were searched from database inception to September 2018. Studies were e...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsThe developed HTA appears to have some utility, but needs evaluation in larger studies. It can potentially be used as a training aid, and as a checklist for evaluating surgical performance.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
Publication date: Available online 15 October 2019Source: The Lancet Respiratory MedicineAuthor(s): Yunpeng Yang, Jianya Zhou, Jianying Zhou, Jifeng Feng, Wu Zhuang, Jianhua Chen, Jun Zhao, Wei Zhong, Yanqiu Zhao, Yiping Zhang, Yong Song, Yi Hu, Zhuang Yu, Youling Gong, Yuan Chen, Feng Ye, Shucai Zhang, Lejie Cao, Yun Fan, Gang WuSummaryBackgroundEnsartinib is a potent new-generation ALK inhibitor with high activity against a broad range of known crizotinib-resistant ALK mutations and CNS metastases. We aimed to assess the efficacy and safety of ensartinib in ALK-positive patients with non-small-cell lung cancer (NSCLC), i...
Source: The Lancet Respiratory Medicine - Category: Respiratory Medicine Source Type: research
Authors: Yang S, Wang D, Xu J, Luo F, Wu W, Zhang Z Abstract Objective: To observe the clinical effect of anterior debridement, decompression, bone grafting, and instrumentation for cervical spinal tuberculosis in four hospitals. Materials and Methods: This research retrospectively analyzed 146 patients with cervical spinal tuberculosis who were treated by anterior debridement, decompression, bone grafting, and instrumentation in four institutions between January 2000 and January 2015. There were 68 males and 78 females with an average age of 31.32 ± 11.69 years. All patients received chemotherapy for 18 mon...
Source: Neurological Research - Category: Neurology Tags: Neurol Res Source Type: research
Authors: Wu T, Peng J, Meng T, Liu Q, Ao X, Lin W, Yin H, Chen J, Pu J, Peng Z, Peng W, Li X, Xiao X, Zhou Q, Zhong Y, Xiao P Abstract Rapidly progressive glomerulonephritis (RPGN), characterized by rapid kidney dysfunction caused by aggressive glomerulonephritis, is usually associated with crescentic glomerulonephritis (CrGN). In the present study, the data from patients with CrGN were retrospectively analyzed at a tertiary medical center in China with the aim of investigating the clinicopathological features and the association of the type of CrGN with the prognosis. The renal biopsies of 49 patients diagnosed wi...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Authors: Song B, Yang Y, Teng X, Li Y, Bai W, Zhu J Abstract A randomized double-blinded controlled trial was performed to explore the association between pre-operative anxiety and intra-operative butorphanol requirement to evaluate the precise sedative requirement and to confirm the sedative effect of butorphanol in patients receiving lower-limb orthopedic surgery. The Amsterdam pre-operative anxiety and information scale and the Ramsay sedation score (RSS) were used to assess the patients' pre-operative anxiety score and sedation state during surgery. Patients were divided into two groups according to their pre-o...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
Publication date: Available online 16 October 2019Source: Journal of the Formosan Medical AssociationAuthor(s): Yu-Chuan Chiu, Yu-Hsuan Lin
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research
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