The combined administration of systemic and topical tranexamic acid for total hip arthroplasty: Is it better than systemic?

CONCLUSION: The combined administration of IV and topical TXA compared with IV alone can decrease total blood loss and the number of blood transfusions required without increasing the risk of DVT or/and PE in total hip arthroplasty. But the statistical analysis and clinical relevance is not significant.
LEVEL OF EVIDENCE: Level I Therapeutic Study.
PMID: 30954338 [PubMed - as supplied by publisher]

Source: Acta Orthopaedica et Traumatologica Turcica - April 2, 2019 Category: Orthopaedics Authors: Gulabi D, Yuce Y, Erkal KH, Saglam N, Camur S Tags: Acta Orthop Traumatol Turc Source Type: research