Exploiting metabolic differences to optimize SSRI dosing in adolescents

(Mary Ann Liebert, Inc./Genetic Engineering News) In a simulated study, exposure to and maximum blood concentrations of two selective serotonin reuptake inhibitors (SSRIs) -- commonly used to treat anxiety and depression in adolescents -- differed depending on whether the teens modeled were poor, normal, rapid, or ultra-rapid metabolizers of the SSRIs.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news