Homoharringtonine Combined with the Heat Shock Protein 90 Inhibitor IPI504 in the Treatment of FLT3-ITD Acute Myeloid Leukemia.

In conclusion, our findings indicate that the combination of HHT and HSP90 inhibitor provides an alternative way for the treatment of FLT3-ITD positive acute myeloid leukemia, especially for relapsed/refractory AML.
PMID: 30953928 [PubMed - as supplied by publisher]

Source: Translational Oncology - April 2, 2019 Category: Cancer & Oncology Authors: Wu Z, Zhuang H, Yu Q, Zhang X, Jiang X, Lu X, Xu Y, Yang L, Wu B, Ma A, Zhang L, Xiao X, Liang Y, Gao R, Shen J, Xu R Tags: Transl Oncol Source Type: research