About Face: Molecular Aberrations in Head and Neck Mucosal Melanomas.

About Face: Molecular Aberrations in Head and Neck Mucosal Melanomas.
Clin Cancer Res. 2019 Apr 05;:
Authors: Shoushtari AN
Abstract
Detailed molecular characterization of a large cohort of mucosal melanomas, most arising from head and neck primaries, suggests that chromosomal translocations and other complex rearrangements have prognostic importance. CDK4 amplification is a frequent event in these rare tumors, and CDK4/6 inhibition may represent a rational clinical trial strategy.
PMID: 30952641 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - April 4, 2019 Category: Cancer & Oncology Authors: Shoushtari AN Tags: Clin Cancer Res Source Type: research