Cerebral cortex impairment in neuromyelitis optica spectrum disorder: A case report and literature review

ConclusionsCortical impairment with leptomeningeal enhancement can be considered an imaging performance component of NMOSD. Serious damage to the blood–brain barrier and Aquaporin-4 antibody (AQP4) may be involved in the process of cortical and leptomeningeal damage. We identified the frontal lobes as being the most susceptible area, especially the cortex adjacent to the cerebral falx. NMOSD cortical lesions may be reversed by methylprednisolone and immunosuppressant treatment.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research