ASAP Integrated Lipidomics and Transcriptomics Characterization upon Aging-Related Changes of Lipid Species and Pathways in Human Bone Marrow Mesenchymal Stem Cells

Journal of Proteome ResearchDOI: 10.1021/acs.jproteome.8b00936
Source: Journal of Proteome Research - Category: Biochemistry Authors: Source Type: research

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Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Fernanda Carrilho de Menezes, Laertty Garcia de Sousa Cabral, Maria Carla Petrellis, Cyro Festa Neto, Durvanei Augusto Maria
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: August 2020Source: Biomedicine &Pharmacotherapy, Volume 128Author(s): Celso Alves, Eurico Serrano, Joana Silva, Carlos Rodrigues, Susete Pinteus, Helena Gaspar, Luis M. Botana, Maria C. Alpoim, Rui Pedrosa
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 30 May 2020Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Zachary Field, Mario Madruga, Steeve J. Carlan, Reem Abdalla, Jordan Carbono, Hareer Al Salihi
Source: Hematology Oncology and Stem Cell Therapy - Category: Cancer & Oncology Source Type: research
Publication date: Available online 30 May 2020Source: Stem Cell ResearchAuthor(s): Liang Shi, Yazhou Cui, Zijuan Qi, Xiaoyan Zhou, Jing Luan, Jinxiang Han
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: October 2020Source: Materials Science and Engineering: C, Volume 115Author(s): Alessandra Salvetti, Gaetana Gambino, Leonardo Rossi, Daniele De Pasquale, Carlotta Pucci, Stefania Linsalata, Andrea Degl'Innocenti, Simone Nitti, Mirko Prato, Chiara Ippolito, Gianni Ciofani
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research
PER2 inhibits proliferation and stemness of glioma stem cells via the Wnt/β‑catenin signaling pathway. Oncol Rep. 2020 May 27;: Authors: Ma D, Hou L, Xia H, Li H, Fan H, Jia X, Niu Z Abstract Glioblastoma is a highly malignant tumor that contains stem‑like cells known as glioma stem cells (GSCs), which lare associated with an increased risk of glioma occurrence, recurrence and poor prognosis. Circadian clock gene, period circadian clock 2 (PER2) expression has been revealed to be inhibited in various types of cancer. However, the precise role and potential mechanisms of PER2 in GSCs remai...
Source: Oncology Reports - Category: Cancer & Oncology Tags: Oncol Rep Source Type: research
In conclusion, AK094629 knockdown attenuated the expression of IL‑1β‑regulated IL‑6 in the SMSCs of the temporomandibular joint by inhibiting MAP3K4. Therefore, AK094629 may be a potential novel therapeutic target for the treatment of temporomandibular joint osteoarthritis. PMID: 32468015 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Targeting protein palmitoylation decreases palmitate‑induced sphere formation of human liver cancer cells. Mol Med Rep. 2020 May 22;: Authors: Chong LW, Tsai CL, Yang KC, Liao CC, Hsu YC Abstract Although non‑alcoholic fatty liver disease (NAFLD) is considered a benign disorder, hepatic steatosis has been proposed to be involved in the tumorigenesis of liver cancer. However, the underlying mechanism for carcinogenesis in fatty liver diseases remains unclear. Cancer stem cells (CSCs) have been hypothesized to serve a key role in tumorigenesis. Tumor formation begins with a subset of heterogeneous ce...
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Authors: Machairaki V Abstract My main research focused in the last years has been the reprogramming of differentiated cell types, such as human fibroblasts, into pluripotent stem cells called induced pluripotent stem cells (iPSCs) and the application of this technology to studies of the nervous system and the diseases that affect it. We have been working on the generation of iPSC lines from Alzheimer's disease (AD) patients using recent developments in reprogramming strategies such as non-integrating episomal vectors to produce virus-free, clinical safe hiPSC. Our study shows that neurons differentiated from these...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Authors: Tsaridou S, Skamnelou M, Iliadou M, Lokka G, Parlapani E, Mougkogianni M, Danalatos RI, Kanellou A, Chlorogiannis DD, Kyrousi C, Taraviras S Abstract Human brain possesses a unique anatomy and physiology. For centuries, methodological barriers and ethical challenges in accessing human brain tissues have restricted researchers into using 2-D cell culture systems and model organisms as a tool for investigating the mechanisms underlying neurological disorders in humans. However, our understanding regarding the human brain development and diseases has been recently extended due to the generation of 3D brain or...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
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