Clinical experience utilizing single-nucleotide polymorphism data captured by FAST-SeqS to reduce the transfer of polyploid embryos

Our FAST-SeqS NGS aneuploidy screening (PGT-A) platform now analyzes single-nucleotide polymorphisms (SNPs) in addition to long interspersed nucleotide elements (LINE-1s). The SNP enhancements permit the detection of all forms of triploidy (e.g., 69,XXX), other forms of polyploidy (e.g., 92,XXXX), haploidy/whole genome uniparental isodisomy (WG-UPiD), and many instances of single-chromosome UPiD, in addition to whole-chromosome and segmental aneuploidy. FAST-SeqS improvements allow for correct classification of abnormalities potentially misclassified previously, which is essential for decreasing molar pregnancy and miscarriage rates.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Poster Presentation Source Type: research